- Spinal cord injury
- Spinal cord stimulator
- Spinal fusion
- Spinal nerves
- Spinal stenosis
- Spindle
- Spindle apparatus
- Spindle oil
- Spindles
- Spine
- Spine of scapula
- Spinel
- Spinning
- Spinning frame
- Spinning jenny
- Spinning mule
- Spinocerebellar ataxia
- Spinodal
- Spinodal decomposition
- Spinor
- Spinosad
- Spinothalamic tract
- Spintronics
- Spiral antennas
- Spiral bevel gear
- Spiral fracture
- Spiral ganglion
- Spiral separator
- Spiral wave
- Spirals
- Spirit lamp
- Spiro
- Spirochetes
- Spirometer
- Spirometry
- Spironolactone
- Spiropyran
- Spirotetramat
- Spirulina
- Splanchnic
- Splash lubrication
- Splash zone
- Splat quenching
- Spleen
- Splenic artery
- Splenic flexure
- Splenic vein
- Splenius capitis
- Splenomegaly
- Splices
- Splicing
- Spline
- Spline interpolation
- Splines
- Splint
- Split
- Split attention effect
- Split graph
- Split interval
- Split radix
- Split-ring resonators
- Splitters
- Splitting field
- Spodumene
- Spoilers
- Spoken dialog systems
- Spokes
- Spondylitis
- Sponge
- Sponge city
- Sponge iron
- Spongin
- Spongiosis
- Spontaneous combustion
- Spontaneous emission
- Spontaneous fission
- Spontaneous magnetization
- Spontaneous parametric down-conversion
- Spontaneous potential
- Spontaneous process
- Spontaneous symmetry breaking
- Spoof surface plasmon
- Spoofing
- Spoofing attacks
- Sporinite
- Sporopollenin
- Sporosarcina pasteurii
- Sports biomechanics
- Sports car
- Sports injuries
- Spot
- Spot facing
- Spot height
- Spot welding
- Spray
- Spray drying
- Spray foam
- Spray forming
- Spray nozzle
- Spray pond
- Spray towers
- Spread
- Spread footings
- Spread spectrum
- Spreading activation
- Spreadsheets
- Spring Boot
- Spring Framework
- Spring Security
- Spring steel
- Springs
- Sprockets
- Sprues
- Sprung mass
- Spur gear
- Spurious correlation
- Sputter deposition
- Sputtering
- Sputum
- Sputum culture
- Spyware
- Squalene
- Squalene epoxidase
- Squalene synthase
- Squamous cell carcinoma
- Squamous metaplasia
- Squamous-cell carcinoma
- Squaraine
- Squaraine dye
- Square antiprism
- Square inches
- Square kilometre
- Square lattices
- Square matrix
- Square metre
- Square mile
- Square planar
- Square pyramid
- Square pyramidal
- Square root
- Square root of 2
- Square root of 3
- Square waves
- Square yard
- Square-integrable functions
- Square-law detector
- Squared deviation from the mean
- Squared deviations
- Squares
- Squaric acid