- Direct injection
- Direct integration
- Direct laser writing
- Direct limit
- Direct linear transformation
- Direct manipulation
- Direct message
- Direct methods
- Direct pathway
- Direct photons
- Direct product
- Direct proof
- Direct reduction
- Direct shear test
- Direct stiffness method
- Direct sum
- Direct thrombin inhibitors
- Direct torque control
- Direct-conversion receiver
- Direct-coupled amplifier
- Direct-current plasma
- Direct-drive
- Direct-drive mechanism
- DirectShow
- Directed evolution
- Directed graph
- Directed set
- Directing groups
- Direction cosines
- Direction finding
- Direction of arrival
- Directional antenna
- Directional couplers
- Directional derivative
- Directional drilling
- Directional freezing
- Directional solidification
- Directional stability
- Directional statistics
- Directionality
- Directivity
- Directory
- Directory Access Protocol
- Directory structure
- Directrix
- Dirichlet Integral
- Dirichlet boundary condition
- Dirichlet distribution
- Dirichlet eigenvalue
- Dirichlet problem
- Dirichlet processes
- Dirty data
- Disaccharides
- Disarticulation
- Disassembler
- Disaster recovery
- Disaster recovery plan
- Disc cutter
- Disc filter
- Disc protrusion
- Discectomy
- Discharge
- Discharge coefficient
- Discharge pressure
- Discharge printing
- Disclinations
- Discography
- Discoid lupus erythematosus
- Disconnector
- Discontinuity
- Discontinuity layout optimization
- Discontinuous deformation analysis
- Discounting
- Discoverability
- Discovery Studio
- Discovery of graphene
- Discrete Morse theory
- Discrete Ordinates Method
- Discrete category
- Discrete choice
- Discrete differential geometry
- Discrete dipole approximation
- Discrete element method
- Discrete event dynamic system
- Discrete event simulation
- Discrete group
- Discrete logarithm
- Discrete manufacturing
- Discrete modelling
- Discrete optimization
- Discrete symmetry
- Discrete topology
- Discrete uniform distribution
- Discrete valuation
- Discrete-event simulation
- Discrete-time
- Discrete-time Markov chains
- Discretization
- Discretization error
- Discriminant
- Discriminative model
- Discriminator
- Disdrometer
- Disease burden
- Disease entity
- Disease management
- Disease resistance
- Disease surveillance
- Disease vectors
- Diseases
- Disfigurement
- Dishevelled
- Dishwasher
- Disinfectants
- Disinfection by-products
- Disintegrins
- Disintermediation
- Disjoining pressure
- Disjoint
- Disjoint sets
- Disjoint unions
- Disjoint-set data structure
- Disjunctive graph
- Disk
- Disk arrays
- Disk drive
- Disk encryption
- Disk laser
- Dislocation creep
- Dislocations
- Dismutase
- Disodium phosphate
- Dispatchable
- Dispatchable generation
- Dispersal
- Dispersants
- Disperse dyes
- Dispersion
- Dispersion point
- Dispersion polymerization
- Dispersion relations
- Dispersion-shifted fiber
- Dispersity
- Dispersive prism
- Displaced threshold
- Displacement
- Displacement chromatography
- Displacement current
- Displacement mapping
- Displacement ventilation