- Discrete valuation
- Discrete-event simulation
- Discrete-time
- Discrete-time Markov chains
- Discretization
- Discretization error
- Discriminant
- Discriminative model
- Discriminator
- Disdrometer
- Disease burden
- Disease entity
- Disease management
- Disease resistance
- Disease surveillance
- Disease vectors
- Diseases
- Disfigurement
- Dishevelled
- Dishwasher
- Disinfectants
- Disinfection by-products
- Disintegrins
- Disintermediation
- Disjoining pressure
- Disjoint
- Disjoint sets
- Disjoint unions
- Disjoint-set data structure
- Disjunctive graph
- Disk
- Disk arrays
- Disk drive
- Disk encryption
- Disk laser
- Dislocation creep
- Dislocations
- Dismutase
- Disodium phosphate
- Dispatchable
- Dispatchable generation
- Dispersal
- Dispersants
- Disperse dyes
- Dispersion
- Dispersion point
- Dispersion polymerization
- Dispersion relations
- Dispersion-shifted fiber
- Dispersity
- Dispersive prism
- Displaced threshold
- Displacement
- Displacement chromatography
- Displacement current
- Displacement mapping
- Displacement ventilation
- Display device
- Display resolution
- Disposable
- Disposable cups
- Dissected plateau
- Dissection
- Disseminated
- Dissimilar friction stir welding
- Dissimilatory metal-reducing bacteria
- Dissimilatory nitrate reduction to ammonium
- Dissimilatory sulfate reduction
- Dissipation
- Dissipation factor
- Dissipative particle dynamics
- Dissipative solitons
- Dissipative systems
- Dissipator
- Dissociation constant
- Dissociation rate
- Dissolution
- Dissolution testing
- Dissolved air flotation
- Dissolved gas analysis
- Dissolved load
- Distal convoluted tubule
- Distal radioulnar joint
- Distal radius fracture
- Distance
- Distance correlation
- Distance education
- Distance field
- Distance geometry
- Distance matrix
- Distance measure
- Distance of closest approach
- Distance transform
- Distance-vector routing protocol
- Distillate
- Distillation
- Distillation columns
- Distilled water
- Distinction
- Distortion
- Distortion function
- Distraction osteogenesis
- Distress
- Distributary
- Distributed algorithms
- Distributed amplifier
- Distributed antenna system
- Distributed artificial intelligence
- Distributed cache
- Distributed computing
- Distributed computing environment
- Distributed databases
- Distributed feedback lasers
- Distributed lag
- Distributed ledgers
- Distributed manufacturing
- Distributed memory
- Distributed objects
- Distributed parameter systems
- Distributed power
- Distributed propulsion
- Distributed shared memory
- Distributed temperature sensing
- Distributed version control
- Distributed-feedback lasers
- Distribution centers
- Distribution fitting
- Distribution function
- Distribution law
- Distribution transformer
- Distributional semantics
- Distributive
- Distributive justice
- Distributive lattice
- Distributive property
- Distributivity
- Distributors
- District cooling
- Disturbances
- Disulfide
- Disulfiram
- Ditches
- Diterpenes
- Dither
- Dithiane
- Dithiocarbamates
- Dithiol
- Dithionite
- Dithiophosphate
- Dithiothreitol