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Pediatric fibrolamellar hepatocellular carcinoma: case report and review of the literature
Published in Acta Chirurgica Belgica, 2021
Laura Depauw, Glenn De Weerdt, Ben Gys, Sofie Demeulenaere, Wouter Mebis, Dirk Ysebaert
Further workup of the case was carried out via magnetic resonance imaging (MRI) which confirmed a subcapsular lesion (5.7 × 4.6 × 4.1 cm) at the transition of liver segments 5, 6 and 8 with signs of recent bleeding (Figure 1). The MRI characteristics were compatible with that of a primary liver lesion in an otherwise healthy liver, suggestive for a fibrolamellar hepatocellular carcinoma (FL-HCC). Positron emission tomography (PET)—computed tomography (CT) confirmed the presence of the liver lesion with a mild to moderate fluorodeoxyglucose (FDG) avidity. No other FDG avid lesions were detected, not intra- nor extrahepatic. Tumor markers (alpha-fetoprotein, carcinoembryonic antigen and beta-human chorionic gonadotropin) were negative.