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Electrospun Collagen Nanofiber Membranes for Regenerative Medicine
Published in Ahmad Fauzi Ismail, Nidal Hilal, Juhana Jaafar, Chris J. Wright, Nanofiber Membranes for Medical, Environmental, and Energy Applications, 2019
Jonathan P. Widdowson, Nidal Hilal, Chris J. Wright
Collagen fibers are deposited and arranged in a linear format during wound closure, and this causes a weakening of the tissue once restored, referred to as scarring, the degree of scar severity is dependent on a wide array of factors, including age (Ashcroft et al. 1998), skin color (Murray et al. 1981), and location (Bayat et al. 2003). This scarring occurs due to the repair, or incomplete regeneration of the tissue (Min et al. 2006b), rather than the regeneration seen in non-injured skin which acts as an exact copy of morphology and functionality (Min et al. 2006a).
Silicone Pressure-Sensitive Adhesives
Published in István Benedek, Mikhail M. Feldstein, Technology of Pressure-Sensitive Adhesives and Products, 2008
Shaow B. Lin, Loren D. Durfee, Alexander A. Knott, Gerald K. Schalau
The use of silicone gels for improving the appearance of scars has been well known for some time. In the year 2000, Posten [23] conducted a metastudy of 27 separate studies and concluded that silicone gel sheeting was superior to other occlusive dressings in the treatment and management of scars, even red and raised scars. Since the publication of the results, the market has seen a proliferation of scar therapies utilizing silicone gel sheeting.
Occupational Dermatosis and Eye Hazard
Published in Ronald Scott, of Industrial Hygiene, 2018
The inner skin layer, dermis, resists tearing or puncture. A meshwork of collagen fibers, rope-like protein structures that are strong without being rigid and unbending, is like a woven cloth, flexible but resistant to tearing. Should damage occur, specialized cells (fibroblasts) produce new collagen to heal the wound. Scars are the result of heavy collagen production.
Bra preferences of breast cancer survivors treated with mastectomy and prosthetic reconstruction
Published in International Journal of Fashion Design, Technology and Education, 2020
Susanne M. Wroblewski, Maureen S. MacGillivray, Chin-I. Cheng
Steligo (2013), an RN and cancer survivor herself, communicates that though surgery can allow one to appear quite normal when dressed, there are several physical anomalies which are likely with reconstruction. Reconstructed breasts are likely to be much more round and flat than natural breasts (Steligo, 2013). If a flap procedure is used in conjunction with implants, breast size will increase and decrease with weight gain or loss. If unilateral mastectomy is chosen, it may be difficult for the surgeon to match the remaining breast; asymmetry is common. Finally, Steligo (2013) reminds those considering mastectomy and reconstruction that scarring is part of the process. Though scars will fade over time, incision sites as well as flap and tissue donor sites will remain scarred. Healing success is very much dependent on age, genetics and proper scar site maintenance.
Fabrication and characterization of the porous duck’s feet collagen sponge for wound healing applications
Published in Journal of Biomaterials Science, Polymer Edition, 2018
Md. Tipu Sultan, Ju Yeon Jeong, Ye Been Seo, Ok Joo Lee, Hyung Woo Ju, Hyun Jung Park, Young Jin Lee, Ji Seung Lee, Soon Hee Kim, Chan Hum Park
Collagen deposition in the wound healing site was observed using Masson’s Trichrome staining (Figure 7). The Colladerm treated group showed the fastest healing stage than DFC sponge until day 14 post wounding (Figure 7). On day 14 we could not observe any contracture in the DFC and Colladerm treated group unlike control group. Although scars mainly result from the failure of the regeneration of the normal skin, the scar may form due to an abnormal alignment of the collagen during the wound healing process [29,30]. The synthesis and deposition of collagen are critical to skin wound healing. MT staining at both 14 and 21 days revealed a much intense blue-stained collagen deposition in the DFC sponge implanted group compared to that in the Colladerm treated group. It was also found that the alignment of the collagen in the DFC treated group was relatively better than that of the Colladerm treated group. These observations suggested that there was more skin regeneration in the DFC sponge implanted group than that of in the Colladerm treated group.
Describing a modern therapeutic drug prepared by in situ decorated gold nanoparticles on starch-modified magnetic nanoparticles to treat the cutaneous wound: a preclinical trial study
Published in Journal of Experimental Nanoscience, 2022
Xiang Li, Hailun Feng, Yonghong Mei, Zeyong Wu, Xiaofen Cai, Zhiqiang Xu, Jia Hui, Zhiyuan Wu
Wound dressing plays an important role in the healing if properly covered it reduces the time for healing and decrease the chances of scar formation. The main objective of the wound dressing is to accelerate the wound healing process by preventing microbial growth, absorbing wound fluid and by maintaining a wet environment around the wound [3–5]. The metallic nanoparticles potentially have some antimicrobial activity that can reduce the growth of microorganisms, when exposed to skin, the coated medicinal herbs are absorbed by the body and provide treatment for a wide range of diseases including hypertension, arthritis, asthma, skin infections, and diabetes [5–7].