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Flexures
Published in Richard Ashton, Barbara Leppard, Differential Diagnosis in Dermatology, 2021
Richard Ashton, Barbara Leppard
Generalised sweating is usually due to an underlying medical condition, e.g. fever, thyrotoxicosis, diabetes, menopause, infections such as TB and HIV, lymphoma, phaeochromocytoma and some drugs e.g. tricyclic antidepressants and tamoxifen.
Vascular Surgery
Published in Tjun Tang, Elizabeth O'Riordan, Stewart Walsh, Cracking the Intercollegiate General Surgery FRCS Viva, 2020
Yiu-Che Chan, John Wang, Julian Wong, Edward Choke, Tjun Tang
What conditions are associated with excessive sweating?Diabetes mellitusHypothyroidismHyperpituitarismPheochromocytomaNeurological conditions (e.g. Parkinson's disease)Reflex sympathetic dystrophy/chronic pain syndromeMalignancyTuberculosis (usually night sweats) and other infectionsDrugs (e.g. propanolol, tricyclic antidepressants, serotonin reuptake inhibitors)Menopause
How do I smell?
Published in Alan Bleakley, Educating Doctors’ Senses Through the Medical Humanities, 2020
Fruity odours on the breath, for example, signal a diabetic crisis. Foul breath may indicate a respiratory tract infection or undiagnosed sleep apnoea, where breathing stops and starts while sleeping, making the mouth very dry. While tolerable body odour is normal, a strong smell could indicate a skin disorder. A number of internal health problems, such as liver and kidney disease and hyperthyroidism, may lead to symptoms including body odours through excessive sweating. Recognising and treating this is one thing, naming it is another – again, shall we stigmatise?
Hyperhidrosis quality of life measures: review and patient perspective
Published in Journal of Dermatological Treatment, 2019
Ros Wade, Julie Jones-Diette, Kath Wright, Alison M Layton, Nerys Woolacott
The HDSS is a disease specific tool considered important for diagnostic use in clinical practice and for research to identify and quantify the severity of disease in patients with hyperhidrosis and also to assess treatment effects over time (3,4). The HDSS allows researchers to measure the impact hyperhidrosis has on those suffering from excessive sweating using a four-point scale:My sweating is never noticeable and never interferes with my daily activities.My sweating is tolerable but sometimes interferes with my daily activities.My sweating is barely tolerable and frequently interferes with my daily activities.My sweating is intolerable and always interferes with my daily activities.
Advances in autoimmune myasthenia gravis management
Published in Expert Review of Neurotherapeutics, 2018
Shuhui Wang, Iva Breskovska, Shreya Gandhy, Anna Rostedt Punga, Jeffery T. Guptill, Henry J. Kaminski
AChE inhibitors (pyridostigmine bromide) retard the hydrolysis of acetylcholine at the neuromuscular junction and thereby increase the chance of activation of existing AChRs at the damaged myasthenic junction. For mild-to-moderate weakness, these are usually the initial treatment [93,94] and for rare patients cholinesterase inhibitor therapy may be the only therapy required [93]. Often when immunotherapies are optimized AChE inhibitors may be discontinued and can be restarted, if symptoms develop again. Adverse effects, in particular nausea, bloating, and diarrhea, limit the use of AChE inhibitors. Excessive sweating is a common complaint of some patients. Respiratory secretions may be increased, which complicates treatment of patients with pulmonary diseases and may actually worsen breathing.
Investigation on aetiological factors in patients with hyperhidrosis
Published in Cutaneous and Ocular Toxicology, 2018
As distinct from primary form, secondary HH develops as a result of an underlying medical condition. Excessive sweating results from several causes such as drug use, infections, endocrine and metabolic disorders, toxins, genetic diseases, malignancies, spinal cord injuries, cardiovascular or respiratory disorders, anxiety or stress, inflammatory skin diseases, or structural defects associated with abnormal sweat glands2,3,30. Half of our patients were in secondary HH group. Like some other investigators, we found pathologies such as hypoglycaemia and hyperglycaemia, thyroid disease, and cardiovascular disease as aetiological factors in this group of patients30–33.