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Overcoming sleep problems
Published in Chris Williams, Roch Cantwell, Karen Robertson, Overcoming Postnatal Depression, 2020
Chris Williams, Roch Cantwell, Karen Robertson
Caffeine is a chemical found in cola drinks, coffee, tea, some hot chocolate and some herbal drinks. It causes you to be more alert. People who have lots of caffeine for several weeks can get addicted to it. It also reduces your sleep quality. There is a real risk that you can get into a vicious circle, in which tiredness causes you to drink more caffeine to keep alert. Then the caffeine itself affects your sleep and worsens the original tiredness. Try not to drink more than five cups of strong coffee or equivalent a day
Caffeine in the modulation of brain function
Published in B.S. Gupta, Uma Gupta, Caffeine and Behavior, 2020
J. Patrick Myers, David A. Johnson, Devon E. McVey
Caffeine is well known for its stimulant properties and is found in foods, beverages, and as a constituent of drug formulations throughout the world. The mechanisms in the brain by which caffeine produces its effects, however, have not been understood until the last decade, with the advent of powerful research tools that have permitted investigators to study the biochemical and neuropharmacological properties of this drug. The intent of this article is to review the scientific literature which is related to the role of caffeine as a modulator of neurotransmission in general, and then to focus specifically on how caffeine affects cholinergic pathways. Finally, a link will be made between the changes in a caffeine-mediated cholinergic neurotransmission and behavioral effects of the drug.
Consciousness, Sleep and Hypnosis, Meditation, and Psychoactive Drugs
Published in Mohamed Ahmed Abd El-Hay, Understanding Psychology for Medicine and Nursing, 2019
Caffeine is the most widely used psychoactive drug in the world. It is found in drinks like coffee, tea, cola drinks, and in chocolate and certain over-the-counter medications. Caffeine is usually used to promote wakefulness, mental alertness, and vigilance. Excess caffeine can produce anxiety, restlessness, and increased heart rate and can disrupt normal sleep patterns and can also contribute to the incidence of sleep disorders, including the NREM parasomnias, like sleepwalking (Cartwright, 2004). There is clear scientific evidence that caffeine is physically addictive. If caffeine intake is abruptly stopped, withdrawal symptoms are experienced: headaches, irritability, drowsiness, and fatigue can last a week or longer (Juliano & Griffiths, 2004; Reissig, Strain, & Griffiths, 2009).
Effect of simultaneous coffee/caffeine and ethanol administration on sperm quality and reproductive hormones: an experimental study in Sprague Dawley rats
Published in Drug and Chemical Toxicology, 2022
J. S. Aprioku, R. Boms, D. O. Ife-tubiyele
Alcohol is a psychoactive substance widely consumed by the young and old globally. It is capable of causing abuse and dependence which is a major public health concern (Holst et al. 2017). Aside from the availability of a variety of alcohol-containing drinks, alcohol is used in several other food and drug products that are frequently consumed. Caffeine, a central nervous system stimulant, is used widely, particularly among students and youths to remain alert and awake. Like alcohol, caffeine consumption is socially acceptable and has abuse potential (Cecile et al. 2016, Watson 2017). Caffeine is contained in a considerable number of products which are readily available and frequently consumed, like beverages and foods (e.g., coffee, tea, and cocoa beans), kola nuts, many popular soft drinks (e.g., Coca-Cola, Pepsi, etc.), sweets, ice-creams, cakes, and chocolates. It is also added in many drug preparations like over-the-counter drugs including, analgesics, diet-aids, and cold/flu remedies.
Nutraceutical Potential of Diet Drinks: A Critical Review on Components, Health Effects, and Consumer Safety
Published in Journal of the American College of Nutrition, 2020
Shareen Banga, Vikas Kumar, Sheenam Suri, Manisha Kaushal, Rasane Prasad, Sawinder Kaur
Caffeine: Caffeine (1, 3, 7 trimethylxanthine) is an alkaloid belonging to methyl xanthine family. It is naturally present in the seeds, leaves, and fruits of more than 63 plant species (28) and possesses a bitter taste. Caffeine is a chief component in DDs as it provides a pleasurable sharp taste. It acts as a stimulant. Caffeine is included in the GRAS (generally recognized as safe) list as it is used in beverages like cola in accordance with the good manufacturing practices, but the level should not exceed 200 ppm, which corresponds to 71 mg of caffeine per 12-ounce serving of cola-type beverages (29). Caffeine when administered gets readily absorbed in the body and it reaches the brain after 5 minutes of consumption (30) and is also eliminated with an average half-life of 5 hours from the body (31). Beneficial effects of caffeine include reduced risk of diabetes, liver injury (32), Parkinson’s disease, and Alzheimer’s disease (33); improved psychomotor performance; and alleviated mood and improved overall immune response (32) (Table 3). On the other hand, it may pose many adverse effects on the body, such as causing addiction (105), coronary artery disease, osteoporosis, anemia, gastritis, anxiety, insomnia (30), and stillbirths (Table 4). The U.S. Food and Drug Administration (FDA) recommended caffeine intake for healthy adults up to 400 mg/d.
Effects of a Multi-Ingredient Energy Supplement on Cognitive Performance and Cerebral-Cortical Activation
Published in Journal of Dietary Supplements, 2019
Marcos Daou, Julia Montagner Sassi, Matthew W. Miller, Adam M. Gonzalez
Caffeine has been shown to increase self-reported alertness, improve mood, and enhance psychomotor and cognitive performance (Smith, 2002). However, in addition to caffeine's synergistic effects with L-theanine, theacrine may act synergistically with caffeine. Theacrine administration appears to enhance locomotor activity in a dose-dependent manner, mediated by both adenosine and dopamine systems (Feduccia et al., 2012). Kuhman, Joyner, and Bloomer (2015) demonstrated that the combination of theacrine and caffeine favorably impacts multiple subjective feelings related to energy and mood compared to caffeine alone and placebo. An acute dose of theacrine (200 mg) alone also has been shown to promote a significant increase in energy, a reduction in fatigue, and a trend (p = .07) toward improved concentration compared to a placebo (Habowski, Sandrock, Kedia, & Ziegenfuss, 2014). Although the potential efficacy of theacrine supplementation is promising, more research is warranted on its isolated and synergistic effects. In the current study, MIES-1 and MIES-2 contained 25 mg and 50 mg of theacrine, respectively, which may have also had a significant impact on our findings.