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Bone Health
Published in Carolyn Torkelson, Catherine Marienau, Beyond Menopause, 2023
Carolyn Torkelson, Catherine Marienau
Caffeine: Whether it comes in coffee or colas, caffeine is a weak diuretic that causes calcium loss via the kidneys. Caffeine intakes of more than 300 mg per day have been shown to accelerate bone loss in older postmenopausal women. However, one to two cups of coffee a day are not harmful.
Lifestyle and Environment
Published in Wilmer W Nichols, Michael F O'Rourke, Elazer R Edelman, Charalambos Vlachopoulos, McDonald's Blood Flow in Arteries, 2022
Coffee is a complex mixture of compounds that may have variable (and often unidentified) effects on the cardiovascular system. However, the effects of coffee are often confused with the effects of caffeine, the methylated xanthine derivative. On the other hand, caffeine, consumed in coffee, tea and soft drinks, is the most widely used pharmacologically active substance in the world, and investigation of its effects is worthwhile in its own right. It should be stressed, therefore, that coffee and caffeine are not interchangeable terms and that results of studies should be interpreted in the context of the particular beverage/substance investigated. Results of studies on coffee consumption are equivocal, varying from a positive to a neutral or to even a J- or a U-shape association with CVD risk (Lopez-Garcia et al., 2008). In a large study, based upon self-reported drinking habits, two or more cups of coffee per day seemed to reduce all-cause mortality in women (but not in men), primarily due to a reduction in cardiovascular mortality (Lopez-Garcia et al., 2008). Similar findings were noted with decaffeinated coffee, suggesting a beneficial effect from a component other than caffeine. Interestingly, regular caffeine intake increases blood pressure, but when ingested through coffee, caffeine has a small effect on blood pressure (Noordzij et al., 2005). The rate of caffeine metabolism through genetic predisposition may be an important determinant of the effect of coffee intake on coronary heart disease risk and may account for these discrepancies in outcomes of studies.
Chemopreventive Agents
Published in David E. Thurston, Ilona Pysz, Chemistry and Pharmacology of Anticancer Drugs, 2021
Cafestol is a diterpenoid found in coffee beans and is considered responsible for some of the alleged pharmacological properties of coffee. Coffea arabica beans contain on average 0.4–0.7% cafestol by weight, with unfiltered coffee drinks such as French press and Turkish or Greek coffee containing the highest concentrations, in comparison to filtered coffee drinks such as drip brewed coffee where cafestol is present in negligible amounts. The inverse (i.e., protective) relationship between the amount of coffee consumed and the risk of certain cancers has been widely investigated and documented, but the significance of the effect and the possible mechanisms behind them remains uncertain.
Association of coffee and genetic risk with incident dementia in middle-aged and elderly adults
Published in Nutritional Neuroscience, 2022
Yuan Zhang, Hongxi Yang, Shu Li, Zhi Cao, Wei-Dong Li, Tao Yan, Yaogang Wang
Coffee is one of the most consumed beverages worldwide and is generally considered to be safe or even beneficial to health. However, previous studies have provided inconsistent conclusions on the role of coffee consumption in the development of dementia. Experiments in mouse models of Alzheimer’s disease have demonstrated beneficial effects of coffee, with improvements in cognition in treated animals [16,17]. Results from epidemiological studies in humans, however, have been inconclusive, with some studies suggesting an inverse association between coffee consumption and the risk of dementia [18], and others pointing to a lack of any association [19,20]. There remain concerns about whether heavy intake (> 6 cups/day), particularly among those with an elevated genetic predisposition for dementia, increase risk of dementia and its subtypes. In addition, most previous studies have focused on total coffee instead of examining coffee types separately.
Effects of acupressure, gum chewing and coffee consumption on the gastrointestinal system after caesarean section under spinal anaesthesia
Published in Journal of Obstetrics and Gynaecology, 2021
Derya Kanza Gül, Ayça Şolt Kırca
Coffee is a widely consumed beverage around the world. Coffee positively affects the human body, including the cardiovascular system and the central nervous system (George et al. 2008). In the literature, coffee consumption has been proved to have positive effects on GIS movements in the postoperative period and to improve bowel movement (Brown et al. 1990; Müller et al. 2012; Goymen et al. 2017; Rabiepoor et al. 2018). In the literature, there are also a great number of studies emphasising that early oral liquid intake contributes to the early recovery of bowel function. (Yaghmaee et al. 2010; Mulayim et al. 2008; Aydin et al. 2014; Jalilian and Ghadami 2014; Macones et al. 2019). In their study conducted with 140 primiparous pregnant women, Jalilian et al. compared the effects of oral liquid food intake at the postoperative 2nd and 8th hours and found that bowel function improved earlier in the group in which oral intake started at the postoperative 2nd hour, and that their gastro intestinal complication rates were not statistically higher (Jalilian and Ghadami 2014).
Sleep habits, circadian preferences and substance use in a Mexican population: the use of the Morningness-Eveningness-Stability-Scale improved (MESSi)
Published in Chronobiology International, 2020
Arturo Arrona-Palacios, Juan F. Díaz-Morales, Ana Adan, Christoph Randler
Caffeine consumption is somewhat inconclusive. Usually, caffeine has a positive influence on cognitive performance and well-being (Adan and Serra-Grabulosa 2010; Smith 2002), which could enhance especially the early morning period. There may also cause and effects in two directions. First, people with higher eveningness may drink more coffee in the morning to get fully awakened. Also, drinking coffee in the morning may produce a higher morning affect. Another interpretation may occur because evening caffeine intake alters the circadian clock (Burke et al. 2015), which may shift people with a late caffeine intake toward eveningness. This request further experimental studies with morning types/evening types coffee choosers and non-choosers as well as studies asking for the specific clock times for coffee intake.