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Herbs with Antidepressant Effects
Published in Scott Mendelson, Herbal Treatment of Major Depression, 2019
In a Brazilian study, it was found that consumption of yerba mate at least once a week during pregnancy caused neither prematurity nor smallness for gestational age. No other adverse effects were reported.14 The Physicians’ Desk Reference for Nonprescription Drugs and Dietary Supplements recommends that pregnant women limit their intake of mate such that caffeine intake remains below 300 mg daily.15
Hallucinogens, CNS Stimulants, And Cannabis
Published in S.J. Mulé, Henry Brill, Chemical and Biological Aspects of Drug Dependence, 2019
The best known of all the heterocyclic stimulants is the ubiquitous purine, caffeine. It is a mild euphoriant, yet by no means can be called a psychotomimetic and is a major component of a large number of socially acceptable drinks, yet it cannot gracefully be classified as a drug. Coffee and tea are major sources (containing perhaps 2% caffeine) found in our society; cacao, Maté, and kola are drinks of comparable strength used elsewhere.
Mode of Action of Selected Botanicals That Lower Blood Glucose
Published in Robert Fried, Richard M. Carlton, Type 2 Diabetes, 2018
Robert Fried, Richard M. Carlton
Yerba mate tea is made from the leaves of mate, Ilex paraguariensis (Aquifoliaceae), which is gaining popularity in South America. A study published in the journal Phytomedicine aimed to determine the effects of an aqueous extract of mate (pronounced ma-tay) on metabolic syndrome features in a metabolic syndrome model Tsumura Suzuki obese diabetic mouse.
Stress and its contribution to the development of depression symptoms are reduced in caregivers of elderly with higher educational level
Published in Stress, 2021
Karstyn Kist Bakof, Laura Morais Machado, Gabriela Rocha Iensen, Sophia Iwersen Faria, Ismália Silva Rodrigues, André Passaglia Schuch, Natielen Jacques Schuch, Carina Rodrigues Boeck
The 24-hour dietary recall is the most used method worldwide to obtain food consumption reports. It consists of an interview conducted by a nutritionist to obtain information to define and quantify the food consumed in the past 24 hours. The participants answered the 72-hour recall for three days, to obtain a better estimate of their caffeine intake. Caffeine intake was calculated according to averages published on the United States Department of Agriculture data base and the values considered in the analyses followed the following standardizations: 85 mg/cup of brewed coffee (240 mL); 75 mg/cup of instant coffee (240 mL); 40 mg/cup of espresso coffee (30 mL); 3 mg/cup of instant coffee (30 mL); 30 mg/cup of black tea (240 mL); 25 mg/cup of green tea (240 mL); 40 mg/cup of mate tea (240 mL); 40 mg/240 mL of the popular South Brazilian yerba mate beverage “chimarrão”; 40 mg/335 mL of cola soda drink; 4 mg/335 mL of guarana soda drink; 80 mg/250 mL of energy drink; 6 mg/spoon of chocolate soluble powder (11 g); 6 mg/30g of solid milk chocolate; and 20 mg/30 g of solid dark chocolate. These values are considerate typical amounts according to the International Food Information Council Foundation. It is important to note that the nutritional information tables of foods currently sold in Brazil do not include information on the amount of caffeine as a micronutrient.
The Inflammatory Potential of Diet is Associated with Breast Cancer Risk in Urban Argentina: A Multilevel Analysis
Published in Nutrition and Cancer, 2021
Camila Niclis, Nitin Shivappa, James R. Hébert, Natalia Tumas, María del Pilar Díaz
Effects of diverse dietary components on inflammation have been identified over the last several years (39, 40); however, scarce evidence exists on the inflammatory effects of the overall diet on cancer risk mainly for those diets that were already recognized as monotonic. Through the Argentinean Household Surveys, it was found that only ten foods contribute to half of the daily calories: bread, sunflower oil, beef, sugar, noodles, rice, wheat flour, sweet cookies, and sugar-sweetened drinks. By contrast, fruits and vegetables contribute little to daily caloric intake (41). Dietary habits of Argentineans are characterized by a high consumption of animal proteins and fats, mainly from red meats (frequently grilled). In addition, the intake of wine and the typical infusion known as “mate” (which contains caffeine) is habitual, while there is a low consumption of fruits and vegetables and fish intake is sporadic (26). Particularly in women, the main dietary pattern identified in Córdoba included fatty meats, bakery products and vegetable oil and mayonnaise as dominant foods groups and it was associated with a higher risk of BC. Of the other three patterns found, the ‘Rural’ (processed meat) and ‘Starchy’ patterns (refined grains) also were positively associated. By contrast, the ‘Prudent’ pattern (fruit and non-starchy vegetables group) was negatively associated with an increased risk of BC (27). Notably, foods groups predominant in the main patterns are rich in pro-inflammatory components (fat -mainly saturated-, high glycemic index carbohydrates); likewise, there is a remarkable lack of foods/nutrients with anti-inflammatory properties (28).
The involvement of multidrug and toxin extrusion protein 1 in the distribution and excretion of berberine
Published in Xenobiotica, 2018
Ling Xiao, Yaru Xue, Cuifeng Zhang, Le Wang, Yunfei Lin, Guoyu Pan
In this research, using in vitro and in vivo experiments, we discovered that BBR is a substrate of MATE1 and that hepatic and renal rMate1 play the important roles in pharmacokinetics of BBR. Taken together, our data further elucidate the mechanism underlying the hepatobiliary and kidney distribution of BBR, and this study could facilitate the identification of strategies for improving the pharmacological effects of BBR. A schematic representation of the transport mechanism of BBR in the liver and kidney is shown in Figure 5. Furthermore, the present research may pave the way for new discoveries in future MATE-related studies. Further studies are necessary to evaluate the risk of MATE1-mediated DDIs of BBR with other drugs in clinical settings.