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Your Voice of Self-Advocacy
Published in Carolyn Torkelson, Catherine Marienau, Beyond Menopause, 2023
Carolyn Torkelson, Catherine Marienau
During our appointment, Susan seemed in a quandary, expressing conflicting beliefs and feelings. “I know I need hormone therapy, but I was hoping to do this naturally. But I have tried everything, and nothing is helping.” Susan’s fears had also been reinforced by a friend’s opinion: “Oh, you don’t want to take hormones—they can cause breast cancer. Medications are not natural.” When I asked Susan to share her concerns about taking hormones, her list was typical of what I have heard from many women: I feel like a failure if I “give in” to medication. Menopause is a natural process that I should be able to control. I am disappointed in myself for not being able to manage these symptoms.I am not the kind of person who takes medication. Both my mother and sister went through menopause without hormones.I’m worried about the risk of breast cancer, even though nobody in my family has had breast cancer, and the Women’s Health Initiative study reassured me that the increased risk of breast cancer in the first few years is low.
Clinicians' Perspective in the Use and Adaptability of the Latest Methods of Diagnosis and Treatment for Cancers in Women
Published in Shazia Rashid, Ankur Saxena, Sabia Rashid, Latest Advances in Diagnosis and Treatment of Women-Associated Cancers, 2022
Cervical cancer is a serious concern to a women’s health, with incident cases of 604,127 and mortality rate of 341,831 individuals worldwide [9]. The control of this disease comes with the intervention of screening, meaning the early detection of precancerous changes in women. Various screening programmes are being encouraged at the central level to check for the high prevalence of human papillomavirus (HPV) infection and incidence of cervical precancer and invasive cancer. Since this is one cancer which has a long latent period and the fact that “precancerous lesions are curable,” there is a huge responsibility on the clinicians to timely diagnose cervical cancer in its precancerous stage by the available screening methods.
Physical Activity for Women
Published in Michelle Tollefson, Nancy Eriksen, Neha Pathak, Improving Women's Health Across the Lifespan, 2021
Ginger Garner, Wendy Farnen Price
The key guidelines for older healthy women and men are identical (Table 2.1). However, aerobic activity and muscle strengthening are of additional importance with respect to women’s health to prevent or address osteoporosis since incidence rates are higher for women. The non-communicable disease (NCDs) section in supplemental materials will provide an overview of PA prescription in adult and older adult women with chronic or persistent conditions. See Table 2.5 for best fit examples of moderate-intensity aerobic physical activities for older women.1
Identification of T cell-related biomarkers for breast cancer based on weighted gene co-expression network analysis
Published in Journal of Chemotherapy, 2023
Breast cancer is a chronic disease threatening women’s health. In 2020, female breast cancer ranked the fifth among all cancers regarding mortality [1]. Breast cancer is a multi-factorial disease with no specific conclusion in the context of its aetiology in the medical field, so only traditional surgery, radiotherapy, chemotherapy and endocrinotherapy strategies can be used in the treatment of breast cancer [2]. Currently, subtyping breast cancers into ER+, HER2+ and triple negative (ER−, PR−, HER2−) is fundamental for disease treatment [3]. For the first two breast cancer subtypes, anti-oestrogen therapy and HER2-targeted agents are respectively effective [4, 5], but for the triple-negative breast cancer (TNBC), chemoradiotherapy is usually the primary treatment regimen [6]. Therefore, exploring new therapeutic approach to improve therapy for breast cancer is of great value.
Clearance of HR-HPV within one year after focused ultrasound or loop electrosurgical excision procedure in patients with HSIL under 30
Published in International Journal of Hyperthermia, 2022
Yi Qin, Qing Li, Xunyu Ke, Yan Zhang, Xiaoling Shen, Wenping Wang, Qiuling Shi, Chengzhi Li
Cervical cancer ranks second among malignant tumors as a lethal disease among women and poses a great threat to women’s health and life, with the morbidity increasing in younger populations [1]. A large number of studies have confirmed that persistent high-risk human papillomavirus (HR-HPV) infection is closely related to high-grade squamous intraepithelial lesion (HSIL) or cervical intraepithelial neoplasia grades 2–3 (CIN 2–3) and that HR-HPV is an important factor for the progression of CIN 2–3 to invasive cervical cancer [2]. Human papillomavirus (HPV) is a common sexually transmitted infection in life with the peak incidence observed among sexually active women [3]. The major peak of HPV infection occurs in women aged 26–30 years [4], who are more likely to be infected with the high carcinogenic types [5].
Squamous cell carcinoma antigen combined with HPV-16 infection in predicting high-grade squamous intraepithelial lesions of the cervix
Published in Journal of Obstetrics and Gynaecology, 2022
Guanglei Zhong, Yuhan Wang, Shixian Yao, Xingyu Fang, Rongchun Lin, Zhongqiu Lin, Yongpai Peng, Tingting Yao
Cervical cancer is the second most common malignancy that affects women’s health in the world. Standard treatment concurrently focussed on surgery, radiotherapy and platinum-based chemoradiation. However, the five-year survival rate of cervical cancer is only 66% (Franco et al. 1999). Hence, early screening of cervical pre-cancerous lesions is of vital importance, it might identify and effectively interfere those patients who would finally develop cervical cancer. Among multiple pre-cancerous lesions, high-grade cervical intraepithelial neoplasia constitutes the major part. Screening methods based on HPV and TCT were highly recommended by the updated American society of clinical pathology screening guidelines for the early detection of cervical cancer and its precursors (Walboomers et al. 1999). However, the detection rate of patients with high-grade cervical intraepithelial neoplasia was less satisfactory.