Atypical and early symptoms of sporadic Creutzfeldt – Jakob disease: case series and review of the literature
Published in International Journal of Neuroscience, 2021
Grammatiki Katsikaki, Ioannis E. Dagklis, Petros Angelopoulos, Dimitrios Ntantos, Angeliki Prevezianou, Sevasti Bostantjopoulou
Vision disorders at presentation of the disease appear in 10–20% of cases of sCJD [38], and when visual disturbance is prominent it is called the Heidenhain (occipitoparietal) variant (3.7–10%) [39–44]. These clinical features are attributed to the occipital lobe disease and consist of blurred vision [39,42,44–46], decreased visual acuity [42,47,48], impaired color vision [42], metamorphopsia [45], abnormal visuospatial perception, visual snow [49], autotopagnosia [50], visual neglect, tunnel vision [42], cortical blindness [46,51], visual agnosia, palinopsia [42,52], diplopia and visual fields defects [41,42,47,53–56].