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The vitamins
Published in Geoffrey P. Webb, Nutrition, 2019
Pantothenic acid is a precursor of coenzyme A which is essential for many metabolic processes – note the acetyl CoA in carbohydrate and fatty acid metabolism and the succinyl CoA of the Krebs cycle. The vitamin is widely distributed in food and clinical deficiency is rare. A “burning feet” syndrome has been reported in severely malnourished prisoners of war and in experimental deficiency. Requirements for pantothenic acid are difficult to estimate accurately.
General Practice
Published in Keith Hopcroft, Instant Wisdom for GPs, 2017
Also known as ‘burning feet syndrome’. Again common, though only rarely given this official ‘label’. It causes unpleasant burning sensations in legs and feet, mainly in those over 50 years old and especially at night. A neuropathy blood screen is recommended, but most cases are idiopathic. Neuropathy-type treatments may help.
Acute pain and medical disorders
Published in Pamela E Macintyre, Suellen M Walker, David J Rowbotham, Clinical Pain Management, 2008
Chronic alcohol intake may result in a toxic polyneuropathy involving the sensory, motor, and autonomic components of the nervous system, most likely due to thiamine deficiency and/or a direct neurotoxic effect of ethanol. Classically, alcoholic neuropathy presents as a slowly progressive, symmetrical, painful peripheral neuropathy, principally affecting the lower limbs in a “stocking (and glove) distribution.” A “burning feet syndrome” associated with allodynia, lancinating pains, and sensorimotor disturbance is common. Alcoholic neuropathy may also present in a rapidly progressive acute form, sometimes mimicking GBS.33 Acute pain management is based on alcohol abstinence (and the treatment of withdrawal), administration of parenteral thiamine, and provision of analgesia, including the use of antineuropathic agents such as mexiletine.34 There is a trend toward improvement in pain with thiamine supplementation35 and lumbar sympathectomy has also been used successfully for pain management.36
Peroneal neuropathy and bariatric surgery: untying the knot
Published in International Journal of Neuroscience, 2020
Mohamad Y. Fares, Zakia Dimassi, Jawad Fares, Umayya Musharrafieh
Neurological complications following BS can present prominent functional impairment in the patient. These complications include: burning feet syndrome, peripheral neuropathy, myotonic syndrome, Wernicke-Korsakoff encephalopathy, and lumbosacral plexopathy [14]. Out of these neurological complications, peripheral neuropathy stands as the most prevalent, with some studies presenting incidence rates reaching up to 16% of BS patients [14].