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Lifestyle Medicine in Menopause and Bone Health
Published in Michelle Tollefson, Nancy Eriksen, Neha Pathak, Improving Women's Health Across the Lifespan, 2021
Vasomotor symptoms are very common in the perimenopause and menopause, with 60% of women experiencing hot flashes, 48% enduring night sweats, and 41% reporting insomnia. Typically, vasomotor symptoms develop 1–2 years before periods cease except in cases of surgery, chemotherapy, or radiation therapy-induced menopause, in which vasomotor symptom onset is abrupt. Estrogen deficit is the culprit, but there also appears to be thermoregulatory involvement. It is somewhat counterintuitive that women with higher levels of body fat report more severe hot flashes yet the association remains. Weight loss has been associated with a decrease in number and severity of hot flashes.2
Autonomic Nervous System Disorders
Published in Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, Joanna M. Wardlaw, Hankey's Clinical Neurology, 2020
The most common clinical manifestations of autonomic dysfunction are: Postural (orthostatic) hypotension.Erectile and ejaculatory dysfunction.Bladder dysfunction.Abnormalities of sweating.Vasomotor disturbances.
More than bones: hormone replacement therapy for mind and body
Published in A. R. Genazzani, Hormone Replacement Therapy and Cancer, 2020
During the climacteric and during the early postmenopausal years, vasomotor symptoms increase in frequency and intensity. A recent cross-sectional survey in a cohort of 6648 women, aged between 47 and 54 years, confirmed that postmenopausal women experience significantly more hot flushes, vaginal dryness, dyspareunia and insomnia than pre- and perimenopausal women, and perimenopausal women have significantly more hot flushes than premenopausal women6.
Psychometric properties of the French Hot Flash Related Daily Interference Scale (HFRDIS)
Published in Climacteric, 2023
I. Cavadias, R. Rouzier, M. Milder, C. Bonneau, J. Mullaert, D. Hequet
The menopausal transition in women is associated with a fluctuation in hormones produced by the ovaries. It is induced by a progressive decrease, until total cessation, of ovarian activity at menopause. These hormonal changes translate into more or less significant symptoms reflecting estrogen deficiency at menopause. The main symptoms reported by patients are vasomotor symptoms, vaginal discomfort associated with vulvovaginal atrophy, and sleep and mood disorders. Vasomotor symptoms, including hot flashes and night sweats, are very common. Hot flashes affect approximately 80% of postmenopausal women, 25% of whom in a very disabling way [1]. These symptoms last on average 5–7 years but can last beyond 10 years [2,3]. The frequency and intensity of hot flashes are extremely variable depending on the individual and can significantly affect quality of life.
Association of menopausal status and symptoms with depressive symptoms in middle-aged Chinese women
Published in Climacteric, 2022
X. Y. Wang, L. H. Wang, J. L. Di, X. S. Zhang, G. L. Zhao
Over the last two decades, the relationship between menopausal symptoms and depressive symptoms has been examined by a number of studies. A systematic review reported a bidirectional association between vasomotor symptoms and self-reported depressive symptoms during perimenopause [11]. Data from the Study of Women’s Health Across the Nation (SWAN) suggested that increased depressive symptoms were more likely to occur among women with vasomotor symptoms even after adjusting for psychosocial factors and testosterone levels [12]. In addition, a multicenter prospective cohort study also demonstrated that there is a strong dose-dependent association between vasomotor symptoms and the likelihood of depressed mood among middle-aged women from the UK, the USA, Australia and Japan [13]. However, previous studies have mostly focused on vasomotor symptoms such as hot flashes and night sweats. The association of other menopausal symptoms, including insomnia, skin formication and urogenital symptoms, with depressive symptoms remains unclear.
Assessment of the effects of menopause on semicircular canal using the video head impulse test
Published in Journal of Obstetrics and Gynaecology, 2021
Ozlem Banu Tulmac, Gokce Simsek
The study groups were formed after determining whether the patients were at reproductive, early menopausal or late menopausal according to the STRAW staging system. The STRAW staging system is taken as the gold standard for characterising reproductive ageing on the basis of the reproductive years through menopause; it considers reproductive years, menopausal transition, perimenopause, final menstrual period and postmenopause, as well as bleeding patterns, endocrine findings and symptoms (Harlow et al. 2012). Natural menopause is defined as the permanent menstrual period cessation, and it is determined retrospectively after a woman has experienced amenorrhoea for 12 months without any other evident pathological or physiological cause (Naçar et al. 2007). Surgical menopause begins with the surgical removal of the ovaries (Kıran et al. 2011). Vasomotor symptoms are used to describe symptoms such as hot flashes. Early menopause was defined as 1–6 years after cessation of menstruation, longer intervals were considered as late menopause.