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Diagnostics of Functional Abnormalities in the Microcirculation System Using Laser Doppler Flowmetry
Published in Andrey V. Dunaev, Valery V. Tuchin, Biomedical Photonics for Diabetes Research, 2023
Irina A. Mizeva, Elena V. Potapova, Elena V. Zharkikh
The main function of the microcirculation is to transport blood and substances to and from tissues. When the blood moves along the capillary, a huge number of water molecules and dissolved particles diffuse in one direction and in the other through the capillary wall, ensuring constant mixing of the tissue fluid and plasma. The permeability of capillaries for various substances is different and depends on the size of their molecules and the type of capillaries themselves. One of the most important purposes of delivering oxygen to the tissues is achieved by blood transport. Cells are constantly in need of oxygen, which they receive by diffusion from the blood through the interstitial fluid. The primary function of the blood is to deliver oxygen to tissues. The circulatory system pumps oxygen-rich blood through the capillary network. The microcirculatory system is organized in such a way that all cells have at least one adjacent capillary for diffusive oxygen exchange, and red blood cells deliver oxygen to the tissues as they pass through the capillaries [24].
Motion of blood in the venous system—novel findings
Published in Dinker B. Rai, Mechanical Function of the Atrial Diastole, 2022
Arterial pressure is dependent upon positive pressure measurement and applicable only to the arterial limb of the circulatory system. In the venous limb circulation is in collapsible tubes and operated by negative pressure. The circulatory system consists of the heart and arterial, capillary, and venous limbs and they operate as one system. A common parameter has to be found and used to understand the hemodynamics of the whole system. This study is an attempt to find an alternative parameter applicable to the whole system as circulation of blood is the sign of life and its main functional feature. Maintaining a particular average velocity in the whole system is a necessity for the “milieu interior” of the body and is dependent upon a coordinated function of all four limbs. Understanding this aspect and getting a grip on the measurement of velocity as a parameter to know the changes in hemodynamics can help in the diagnosis, treatment, and prognosis of the various diseases of cardiac, arterial, capillary, and venous origin. It also may be an important parameter of the future. This study is based on the direct measurement of velocity of the blood, which may prove to be a better parameter in the future and open new doors in this direction.
Delivery of Herbal Cardiovascular Drugs in the Scenario of Nanotechnology: An Insight
Published in Mahfoozur Rahman, Sarwar Beg, Mazin A. Zamzami, Hani Choudhry, Aftab Ahmad, Khalid S. Alharbi, Biomarkers as Targeted Herbal Drug Discovery, 2022
Kumar Anand, Subhabrata Ray, Md. Adil Shaharyar, Mahfoozur Rahman, Rudranil Bhowmik, Sanmoy Karmakar, Monalisha Sen Gupta
Obesity also has an indistinguishable role towards many of the CVDs. An unhealthy lifestyle and nutritional disorders can lead to obesity and it further precipitates diverse clinical situations such as atherosclerosis, renal disorders, HTN, etc. (John et al., 2002). Many circulatory system disorders can be possibly caused by obesity such as diabetes and dislipidemia which further leads to stiffness of blood vessels and stroke like conditions. So diet and obesity or both of these in combination (which happens frequently in a sedentary lifestyle) can lead to many serious cardiovascular disorders.
The Effectiveness of a Multi-Sensory Sleep-Promotion Program on Sleep Quality among Hospitalized Older Adults of Thailand: A Quasi-Experimental Study
Published in Behavioral Sleep Medicine, 2023
Amornrat Kaewlue, Samoraphop Banharak, Ladawan Panpanit, Sutin Chanaboon
Back rubs can promote sleep quality (Cinar & Eser, 2012; Khieophung et al., 2011; Panpanit, 2019). This alternative intervention reduces muscle tension and stimulates the circulatory system. Back rub also relaxes the body and makes it free from stress. As a result, the body releases endorphins. However, catecholamines were lowered, and reticular formation functions were suppressed, reducing the body’s alertness. Finally, better sleep is promoted (Liu et al., 2015; Norman, 2015: Pornratshanee et al., 2005). Ayik and Ozden (2018) studied the mixed effects of back massage using lavender oil (aroma) in hospitalized adults and older adults. Our findings from the multi-sensory sleep promotion program were like theirs: the experimental group had fewer awakenings and reported better sleep quality than the control group.
Modelling and simulation of fluid flow through stenosis and aneurysm blood vessel: a computational hemodynamic analysis
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2023
J. V. Ramana Reddy, Hojin Ha, S. Sundar
Blood vessels play an important role in the circulatory system; These are in the form of tubes that carry blood between the heart and all parts of the body. The blood vessel size varies enormously; in the case of arteries, it varies from 1 mm to 8 µm while 1 mm to 20 µm for veins. An artery carries oxidized blood away from the heart, whereas a vein is the blood vessel that collects and transports blood toward the heart. The general appearance of the arteries is rounded lumen, while veins are irregular and often collapse. As compared to arteries, veins are thin-walled vessels with a large and irregular lumen. The diseases of arteries, veins, and lymph vessels alert to blood flow disorders that affect circulation, thus resulting in disturbance in organ function. An aneurysm is a pathological condition. It weakens the blood vessel wall due to the bulging area in that area, resulting in an abnormal widening or ballooning more significant than 50% of the standard diameter. The arteries are mostly exposed to an aneurysm rather than a vein among the several blood vessels.
Characteristics of participants and decliners from a randomized controlled trial on physical activity in patients with rheumatoid arthritis: a retrospective register-based cross-sectional study
Published in Scandinavian Journal of Rheumatology, 2023
T Thomsen, BA Esbensen, ML Hetland, M Aadahl
In Denmark, all hospital contacts, including administrative information, are registered in the Danish NPR by type and contact date. The NPR records primary and secondary diagnoses and treatment procedures using the ICD-10. We extracted information on morbidity as primary and secondary diagnoses. However, as we initially had identified our target population of patients with RA through DANBIO, we excluded the ICD-10 classification codes for RA (M05_0, M05_9, M06_0, M06_9) from 2003 up to 2013, which was the year for commencement of the JR-SB study recruitment. We were interested in the presence of specific diseases in the RA population as suggested by previous research about morbidity in patients with RA (23). Therefore, comorbidity was classified into seven major ICD-10 classification groups of disease: (i) cancer; (ii) endocrine, nutritional, and metabolic diseases; (iii) mental and behavioural disorders; (iv) diseases of the circulatory system; (v) diseases of the respiratory system; (vi) diseases of the musculoskeletal system and connective tissue; and (vii) infectious and parasitic diseases. From the NPR, we also extracted information on the number of days of hospital admission from 2003 to 2013 in all patients with RA.