China
Africa
Explore chapters and articles related to this topic
Agricultural Nanobiotechnology: Current Possibilities and Constraints
Published in Sunil K. Deshmukh, Mandira Kochar, Pawan Kaur, Pushplata Prasad Singh, Nanotechnology in Agriculture and Environmental Science, 2023
Nanobiotechnology finds application in various fields of agriculture but still there are few constraints to this new technology which does not allow it to deliver its full potential. One of the major issues associated with nanobiotechnology is nanotoxicity. Different researchers have different views about nanotoxicity. The views differ because (i) some scientists used easily scoreable parameters like germination rate, root and shoot length, etc., while others used highly complex parameters like cytotoxicity and genotoxicity; (ii) different plant species respond differently to the same nanoparticle; (iii) unrealistically high concentrations of nanoparticles; and (iv) some ignored the requirement for appropriate control. Nano quantitative structure-activity relations (nano-QSARs) predict the cytotoxicity of various metal oxides using in vitro cell-based assays and the adsorption of various molecules onto nanoparticles, an enthalpy descriptor or a biological surface adsorption index, and some studies used computational chemistry to simulate the translocation of nanoparticle (Wang et al., 2016).
Nanobiotechnology: Applications and Future Prospects
Published in Rakesh K. Sindhu, Mansi Chitkara, Inderjeet Singh Sandhu, Nanotechnology, 2021
Tapan Behl, Priya Nijhawan, Arun Kumar, Rakesh K. Sindhu
Nanobiotechnology is still in its initial phase. The field of nanobiotechnology is taking the science of impenetrably small devices closer and closer to reality. The outcome of this growth will, at some point, be so massive that it will perhaps affect nearly all sectors of science and technology. Nanobiotechnology has proposed a wide array of uses in medicine. Drug-delivery systems are only the early stages of the start of somewhat novel. Several disorders may be cured by nanotechnology in the future. Although the outlook of nanobiotechnology in drugs is high and the potential benefits are infinite, the safety of nanomedicine is not fully realized. The use of nanobiotechnology in medical therapeutics needs suitable assessment of its risk and safety factors. Applications of nanotechnology have arisen with a cumulative need of nanoparticles in several areas of food science and microbiology, food processing, food packaging, functional food development, and shelf-life extension of food. Researchers who are against the use of nanobiotechnology also agree that expansion in nanobiotechnology should continue as this sector promises great advantages, but they caution that evaluation should be done to ensure the safety of people. In the future, nanomedicine would play a vital role in the prevention and management of disorders. If everything runs smoothly, nanobiotechnology will, one day, become an inevitable part of our everyday life and will help save many lives.
Recent Advancement of Nanobiotechnology in Cancer Treatment
Published in Rajesh Singh Tomar, Anurag Jyoti, Shuchi Kaushik, Nanobiotechnology, 2020
Nanobiotechnology is the application of nanotechnology in medicine, which rapidly growing the field of interdisciplinary research and involves in diagnosis, treatment, and/or screen any disease at the nanoscale. Cancer nanotechnology is advance biomedical uses of NPs, which are nano level and that are capable of overwhelmed biological obstacles, especially, identify a particular kind of cancer cell, and collect favorably in tumors. NPs have various therapeutic applications like; they have the capability to deal with innovative methods of noninvasive tumor detection, diagnosis, analysis, and treatment. There are many varieties of ligands directed against cancer cells, such as peptides, antibodies, or small molecules, which can be joined with NPs for targeting of tumor-specific antigens and vasculatures substances with great specificity and high affinity. Moreover, diagnostic agents and chemotherapeutic medicines can be combined into their design for more proficient imaging and therapeutic effect of the tumor with less or no side effects. The latest improvements in nanomedicine increase exciting opportunities for forthcoming applications of NPs in personalized health care management of cancer therapy. Nanotechnology has become an empowering expertise for personalized oncology, in which tumor molecular profile of every person and genetic and/or molecular markers for predictive oncology are applied to the prediction of disease development, advancement, and therapeutic outcomes [6].
BSA nanoparticles loaded-methylene blue for photodynamic antimicrobial chemotherapy (PACT): effect on both growth and biofilm formation by Candida albicans
Published in Journal of Biomaterials Science, Polymer Edition, 2020
Jéssica Aparecida Ribeiro Ambrósio, Bruna Cristina dos Santos Pinto, Bruna Graziele Marques da Silva, Juliene Cristina da Silva Passos, Milton Beltrame Junior, Maricilia Silva Costa, Andreza Ribeiro Simioni
Microbial infectious diseases and increased resistance to antibiotics become urgent problems requiring immediate solutions. One promising alternative is the using of nanoparticulate system combined with PACT protocols. In this work, was synthetized BSA nanoparticles for MB encapsulation by desolvation technique. The nanoparticles fabricated were uniform size, spherical shape and size distribution without physical aggregation. BSA nanoparticles have shown to possess promising in vitro antifungal activities and could be effectively used for enhanced and targeted delivery of conventionally used drugs. The synergistic interaction between nanoparticles and MB was reported with enhanced antifungal activity on both growth and biofilm formation by Candida albicans. This work shows that nanobiotechnology is a tool for the development of novel formulations with enhanced therapeutic efficacy, improved drug delivery and low toxicity.
Applications and hazards associated with carbon nanotubes in biomedical sciences
Published in Inorganic and Nano-Metal Chemistry, 2020
Ali Hassan, Afraz Saeed, Samia Afzal, Muhammad Shahid, Iram Amin, Muhammad Idrees
Nanobiotechnology offers vast opportunities to modify and upgrade the fields of medicine-energy, biosensors, and electronics. Benefits from nanotechnology are achieved by modifying the structure of nanomaterials to make them functionalized. One of supreme class of nanomaterials is carbon nanotubes (CNTs).[1,2] The launching of CNTs and recent developments have revolutionized in emerging field of nano-biotechnology and confers immense contributions both in the domain of engineering and basic science.[3,4]
Utilization of Morchella esculenta-mediated green synthesis golden nanoparticles in biomedicine applications
Published in Preparative Biochemistry & Biotechnology, 2021
One of the applications of nanobiotechnology is to effectively treat human cancers. Recent studies have shown that metal nanoparticles (MNPs), silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) in particular, can be used as a diagnostic and therapeutic option for cancer.[4]