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The Mightiness of Nanotechnology: Biomolecular Motors
Published in Paula V. Messina, Luciano A. Benedini, Damián Placente, Tomorrow’s Healthcare by Nano-sized Approaches, 2020
Paula V. Messina, Luciano A. Benedini, Damián Placente
There is a great potential in the way of the application of biomolecular motors in detection and diagnostic devices. This opens up the opportunity to design highly integrated, miniaturized, autonomous detection procedures that, in turn, may allow fast and cheap on-site diagnosis of diseases and recognition of environmental pathogens and contaminants. In chapter 6, many examples were listed around microfluidics machinery and how this technology has greatly improved the efficiency of immunoassays by providing a means for active transport of the analyte through a small detection device. Nevertheless, with the continuous decrease of the detection devices dimensions, it becomes impractical to use microfluidics for active transport because of the need for external pumps and high pressure. The integration of cytoskeletal motor proteins that replace fluidic flow for analyte transport and an energy source (ATP) into the assay solution that make the device completely independent of external power sources might lead to point of care test (POCT) that should be easy to handle as a urine test strip or a home-use pregnancy proof (Korten et al. 2010).
Detection Technology
Published in Rick Houghton, William Bennett, Emergency Characterization of Unknown Materials, 2020
Rick Houghton, William Bennett
The increase in glucose can be detected by a glucose urine test strip (Bayer Uristix Glucose Strips). If the sample already contains a high amount of glucose before the test, the test strip will be overloaded and the small increase in glucose from the melibiose will not be detected. Dipping a glucose strip in the sample before the addition of the melibiose will provide a benchmark for the glucose strip used after the addition of alpha-galactosidase. The test can be performed in less than 30 seconds.
Drug use and pattern of injuries sustained by drivers involved in road traffic crashes
Published in Traffic Injury Prevention, 2021
Parisa Divsalar, Mehrnoosh Mohammadi, Kouros Divsalar
All patients included in this study completed a survey containing demographic information such as age, gender, occupation, education, marital status, type of vehicle and collision (motorcycle with motorcycle, motorcycle with a car, car with car, motorcycle with obstacle, car with obstacle, bicycle with car or a car overturned) and pattern of serious injury. Besides, if a traumatized patient was not able to fill in the information, the research subordinate would assist the patient. The pattern of injury was documented by the help of emergency physicians using a checklist of traumas dividing body to the regions of head and neck, upper limbs chest and abdomen, lower limbs and pelvis, two parts of the body and more than two areas of the body. Serious injuries such as fractures, internal lesions, severe cuts and laceration were included in this study. Moreover, Urine samples were taken from the patients and tested for tramadol, cannabis, amphetamine, methamphetamine, morphine and methadone using one step urine test strips. One step urine test strip is a competitive immunochromatographic test authorized by the Health Reference Laboratory for use in narcotics and psychedelic analysis laboratories.