Cancer staging

Cancer staging

Cancer staging is a process of categorizing patients with a specific type of tumor based on the extent of the tumor and the spread of cancer. This is typically done after a cancer diagnosis and involves using a staging system, such as the TNM staging system, to classify the tumor. Additionally, tumor differentiation scoring may be used to further classify the tumor into categories based on the hierarchy of tumor cell differentiation. The goal of cancer staging is to provide a standardized way to describe the severity of the cancer and guide treatment decisions.From: Imaging for Students [2012], Re-Analysis of Non-Small Cell Lung Cancer and Drug Resistance Microarray Datasets with Machine Learning [2023], Human leucocyte antigen – G gene polymorphism in laryngeal squamous cell carcinoma patients in Mansoura University Hospitals [2021]

Imaging in oncology

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Published in David A Lisle, Imaging for Students, 2012

David A Lisle

Tumours are classified according to organ of origin and histological type. Cancer staging describes a process whereby patients with a specific type of tumour are categorized, depending on tumour extent, into groups. Patients are generally categorized into four stages, although for many tumours some stages have subcategories. With continuing improvements in treatment regimes in oncology, accurate staging of cancer is increasingly important. Purposes of cancer staging include:Definition of the anatomical extent of tumourSelection of appropriate therapyEstimation of prognosisProvision of a pretreatment baseline to allow monitoring of effects of therapy.

Re-Analysis of Non-Small Cell Lung Cancer and Drug Resistance Microarray Datasets with Machine Learning

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Published in Cybernetics and Systems, 2023

Çiğdem Erol, Tchare Adnaane Bawa, Yalçın Özkan

Lung cancer is the leading cause of death in many countries of the world (Jemal et al. 2010). Depending on its histological structure, it is divided into two groups small cell and non-small cell lung cancer. Non-small cell lung cancer (NSCLC) is the most common, accounting for approximately 85% of lung cancers, with a five-year survival rate of approximately 5% (Mendoza et al. 2020). There are 3 subtypes of NSCLC: adenocarcinoma (40%), squamous cell carcinoma (30-35%) including bronchoalveolar carcinoma, and large cell carcinoma (5-15%) (Ma et al. 2005). After the diagnosis of cancer, staging is done according to the spread of cancer. NSCLC has five stages from zero to four. The severity of the disease starts from zero and gradually increases.

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Imaging in oncology

Re-Analysis of Non-Small Cell Lung Cancer and Drug Resistance Microarray Datasets with Machine Learning