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Therapeutic effectiveness
Published in Dinesh Kumar Jain, Homeopathy, 2022
“Most fevers are associated with self-limited infections, such as common viral diseases” (Dinarello & Porat, 2008, p. 120). In lobar pneumonia patients, without treatment, resolution occurs on the eight day. Complete resolution and regeneration take from one to three weeks. Since there is no tissue destruction in lobar pneumonia, the lung parenchyma returns to normal (Heath & Kay, 1976, p. 414).
Tuberculosis in Childhood and Pregnancy
Published in Lloyd N. Friedman, Martin Dedicoat, Peter D. O. Davies, Clinical Tuberculosis, 2020
Lindsay H. Cameron, Jeffrey R. Starke
Children can have lobar pneumonia without impressive hilar lymphadenopathy. If the primary infection is progressively destructive, liquefaction of the lung parenchyma can lead to the formation of a thin-walled primary tuberculosis cavity. Bullous tuberculous lesions rarely occur in the lungs and, if they rupture, can lead to pneumothorax. Erosion of a parenchymal focus of tuberculosis into a blood or lymphatic vessel can result in dissemination of the bacilli and a miliary pattern, with small nodules evenly distributed on the chest radiograph (Figure 18.2).
SBA Answers and Explanations
Published in Vivian A. Elwell, Jonathan M. Fishman, Rajat Chowdhury, SBAs for the MRCS Part A, 2018
Vivian A. Elwell, Jonathan M. Fishman, Rajat Chowdhury
Lobar pneumonia may progress through 4 stages: Congestion (in the first 24 hours) – inflammatory exudateRed hepatizationGrey hepatizationResolution (complete recovery)
A rare case of IgE kappa monoclonal gammopathy of undetermined significance identified in a Swedish female
Published in Scandinavian Journal of Clinical and Laboratory Investigation, 2021
Marcus Fager Ferrari, Konstantinos Lemonakis, Magnus Förnvik Jonsson
The patient was a 41-year-old woman, previously diagnosed with irritable bowel syndrome (IBS), but otherwise fully healthy and without a family history of hematological disorders. In April 2020, she was diagnosed and empirically treated for a lobar pneumonia. No causative infectious agent was identified following microbiological testing. Due to a period of fatigue following the pneumonia, she visited her physician in May 2020 for an additional checkup, including routine laboratory testing. A serum protein electrophoresis (SPEP) (high resolution [HR] buffer, Capillarys 2, Sebia, Lisses, France) was performed, showing an increased beta-2 fraction in the electropherogram (Figure 1). A subsequent serum immunofixation electrophoresis (SIFE) (Hydrasys 2, Sebia) using antisera to Ig heavy chains gamma, alpha, mu and Ig light chains kappa and lambda, showed a band positive for kappa chains (Figure 2(A)). A complementary SIFE including antisera to Ig heavy chains delta and epsilon confirmed the presence of an IgE kappa monoclonal protein (Figure 2(B)). The level of the IgE kappa monoclonal protein identified by SPEP was roughly estimated to 3.6 g/L by relating the area under the curve (AUC) of the monoclonal peak to the AUC of the albumin peak, the levels of albumin being known in g/L. Further routine laboratory testing showed normal results (Table 1).
Breakthrough pneumonia, meningitis and bloodstream infection due to Streptococcus pneumoniae during cefixime therapy
Published in Journal of Chemotherapy, 2019
Novella Carannante, Carlo Pallotto, Mariano Bernardo, Enza Mallardo, Giovanni Di Caprio, Giulia Palmiero, Vittorio Attanasio, Carlo Tascini
A 20 year-old female was admitted for community-acquired pneumonia. The patient suffered from shaking chills, fever and cough for 5 days. The patient was treated with cefixime (400 mg per day) according to her general practitioner’s prescription. Despite this antibiotic therapy, fever and cough persisted. A chest CT scan was performed and revealed a bilateral lobar pneumonia so that the patient was admitted to our hospital. At admission SOFA score was 4 with FiO2 90%, platelets count 140,000/ml, Glasgow coma scale (GCS) 15, Bilirubin 0.8 mg/dl, blood pressure 90/60 mmHg, creatinine 1.7 mg/dl, C-reactive protein (CRP) was 36.6 mg/dl, procalcitonin (PCT) was 18.7 ng/ml, leucocytes count was 10700/mm3, blood cultures were positive for S. pneumoniae. Treatment with ceftriaxone 2 g/day and rifampin 600 mg/day was started with resolution of symptoms in 3 days. Also, blood cultures turned negative in 3 days of treatment. S. pneumoniae antibiogram showed intermediate susceptibility to penicillin (MIC 0.38 mg/L), susceptibility but with increased MIC to ceftriaxone (0.25 mg/L) and MIC for cefixime equal to 4 mg/L. S. pneumoniae was characterized as serotype 14.
Socio-demographic and clinical factors predicting time to presentation for children with pneumonia in Ilorin, Nigeria
Published in Alexandria Journal of Medicine, 2018
Rasheedat M. Ibraheem, Mohammed B. Abdulkadir, Aishat A. Gobir, Wahab B.R. Johnson
Children with bronchopneumonia had a sevenfold increased odd compared with lobar pneumonia of having an early presentation, and a threefold increased odd of intermediate presentation when compared to late presentation. Children with lobar pneumonia have been reported to have a higher frequency of pneumonia related complications and mortality when compared with children with bronchopneumonia.28,29 Therefore, it is expected that children with lobar pneumonia should be brought earlier than children with bronchopneumonia to seek appropriate health care. However, this is contrary to the current study finding which found that children with bronchopneumonia had a sevenfold increased odd compared with lobar pneumonia of having an early presentation, and a threefold increased odd of intermediate presentation when compared to late presentation. This finding may be partly explained by the fact that bronchopneumonia is more commonly seen in the younger aged child compared to lobar pneumonia, and accounted for the majority of the cases recruited which is similar to the earlier report of Johnson et al.28