China
Africa
Explore chapters and articles related to this topic
Antipsychotic Drugs
Published in Sahab Uddin, Rashid Mamunur, Advances in Neuropharmacology, 2020
Harleen Kaur, Ramneek Kaur, Varsha Rani, Kanishka Sharma, Pawan Kumar Maurya
Atypical antipsychotic drugs are used for curing BDs. Specifically, for bipolar mania, these drugs posses’ good tolerability and high efficacy. Nowadays, atypical antipsychotics medications for bipolar mania are used as polytherapy or monotherapy. Usage of antipsychotic drugs is widespread in clinical settings (Benazzi, 2007). A lot of BDs are centralized as antimaniac agents (Purcell et al., 2009). The first antipsychotic drug, that is, olanzapine received Food and Drug Administration (FDA) indication for bipolar mania, in 2000. Subsequently, in 2003 and 2004 FDA approvals were received for risperidone and for compounds like ziprasidone, aripiprazole, quetiapine for indication of bipolar mania.
Tips for clinical practice
Published in Alan Weiss, The Electroconvulsive Therapy Workbook, 2018
Many of these patients have severe psychiatric disorders, including bipolar or unipolar depression with lethal suicide intent, bipolar mania, or schizophrenia with lethal delusions to self-harm or hurt other people. They are not able to function in the community owing to the high risk to themselves and others. Should such patients be pharmacologically or physically restrained with shackles, transported to the treatment area by a large contingent of strong nurses/security guards or all of the above?
Evening wear of blue-blocking glasses for sleep and mood disorders: a systematic review
Published in Chronobiology International, 2021
Landon Hester, Deanna Dang, Christopher J Barker, Michael Heath, Sidra Mesiya, Tekenari Tienabeso, Kevin Watson
The substantial clinical implications of an effective adjunctive non-pharmacological treatment for acute bipolar mania merit further investigation beyond the existing case study and RCT; both found BB glasses are effective. Longitudinal outpatient treatment of bipolar I and II, delayed sleep-phase disorder, and insomnia with blue-blocking glasses is areas of opportunity for future study. Another potential study could involve patients with major depressive disorder that excludes patients using hypnotic medication. Such a study has the potential to determine if the glasses are useful for depression and for the depressive phases of bipolar disorder. Every study analyzed here was performed in adults, making replication of existing studies in pediatric, adolescent, and geriatric patients a possibility.
Bipolar depression: the clinical characteristics and unmet needs of a complex disorder
Published in Current Medical Research and Opinion, 2019
Roger S. McIntyre, Joseph R. Calabrese
Bipolar disorder is a chronic and complex mood disorder that is characterized by an admixture of manic (bipolar mania), hypomanic and depressive (bipolar depression) episodes, with significant subsyndromal symptoms that commonly present between major mood episodes1. Ranked among the leading causes of worldwide disability2, bipolar I disorder has been consistently associated with significant medical and psychiatric comorbidity, premature mortality, high levels of functional disability and reduced quality of life3. The essential feature of bipolar I disorder requires the occurrence of at least one fully syndromal lifetime manic episode, although depressive episodes are common4. Bipolar II disorder requires the occurrence of at least one hypomanic episode and one major depressive episode; it is no longer considered a milder form of bipolar disorder as it is associated with considerable time spent depressed and with functional impairment that accompanies mood instability4. Bipolar disorder with mixed features is a complex presentation in which a mood episode from either the manic or depressive pole is complicated by the presence of subsyndromal but clinically significant symptoms from the opposite pole. Patients with bipolar depression have greater morbidity and mortality than patients with bipolar mania, with depressed patients having a higher risk of suicide, interepisode panic attack and psychosis5.
Impact of psychosis in bipolar disorder during manic episodes*
Published in International Journal of Neuroscience, 2018
Elionor Nehme, Sahar Obeid, Souheil Hallit, Chadia Haddad, Wael Salame, Fouad Tahan
Psychotic symptoms are considered a typical manifestation of severe manic episodes [20,27]. Goodwin showed that 35–60% of manic episodes were accompanied by grandiose delusions, while 18–65% were associated with persecutory delusions, and 7–48% of patients experienced auditory hallucinations, and 19% display formal thought disorder [20]. Racing thoughts, the flight of ideas and distractibility can be present in up to 71% of patients with mania [20]. Hallucinations and delusions are common features of manic episodes, but tend to be brief and fragmented, and often have grandiose, religious or paranoid themes that typically resolve early during recovery phase [11,28]. These symptoms may represent the most prevalent psychotic symptoms in bipolar mania patients which grandiosity is a hallmark feature of mania [13].