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Neurophysiological Perspectives
Published in Marlysa Sullivan, Laurie C. Hyland Robertson, Understanding Yoga Therapy, 2020
Marlysa Sullivan, Laurie C. Hyland Robertson
The term allostasis brings nuance to the concept of stress, differentiating between the systems that need to be stabilized for life (homeostasis) and the processes that maintain that stability in the face of challenge, change, or adversity (allostasis). The dynamic processes of allostasis support homeostasis.
Benefits of Meditation and Yoga in Clinically Depressed Patients
Published in Anne George, Snigdha S. Babu, M. P. Ajithkumar, Sabu Thomas, Holistic Healthcare. Volume 2: Possibilities and Challenges, 2019
Madhuri Tolahunase, Rajesh Sagar, Rima Dada
In stress, exacerbated disorders like depression, stress from psychological, physically external, and physically internal sources result in allostatic load. Various interventions for depression include pharma-cotherapy; psychotherapy, physical therapy, and various mind-body therapies including yoga; and noninvasive and invasive surgical therapies. Ideal interventions reduce allostatic load and shift the regulatory systems toward optimal homeostasis.
Impact of Lifestyle Medicine on Dysglycemia-Based Chronic Disease
Published in James M. Rippe, Lifestyle Medicine, 2019
A. Michael, Jeffrey I. Mechanick
In normal physiology, serum glucose concentration is kept within a specific range during times of fasting, influx (e.g., food consumption), utilization (e.g., physical activity), or stress (e.g., critical illness). This glycemic stability is achieved through a network of cellular/substrate-level, humoral, and hormonal regulatory mechanisms resulting in “glucose allostasis,”15 with many vulnerable pathways that, when subverted, can lead to chronic disease. Allostasis (“stability through change”) is the physiological process that adjusts homeostatic (“resistance to change”) set points to achieve successful adaptation.
Measuring stress: a review of the current cortisol and dehydroepiandrosterone (DHEA) measurement techniques and considerations for the future of mental health monitoring
Published in Stress, 2023
Tashfia Ahmed, Meha Qassem, Panicos A. Kyriacou
In the resistance/maintenance stage, the body continues to activate afferent pathways in a series of allostatic mechanisms, leading to further physiological changes with increased metabolic activity, to restore balance in the organism from the perceived stress (Juster et al., 2010; Mcewen, 2005). In cases of persistent stressors, i.e. chronic stress, the exhaustion stage is reached wherein the energy and resources for prolonged adaptive responses to the stressor are depleted thus, efforts are ceased (Evans, 1950; Mcewen, 2005; Romero & Butler, 2007). Deterioration and “wear and tear” of the body, known as allostatic overload, can lead to immunosuppression, development of metabolic diseases e.g. diabetes and, progression of clinical depression or major depressive disorder (MDD) (Jefferies, 1991; Juster et al., 2010; Mcewen, 2005).
Discrimination and sleep disturbance: how is substance use a mediator for sexual minority men?
Published in Journal of Social Work Practice in the Addictions, 2023
Numerous research studies have identified how stress has a profound impact on sleep processes. National studies on sleep and allostatic load indicate that chronic stress is associated with decreased sleep quality (Chen et al., 2014). While all individuals experience common stress, individuals from minority groups (e.g., racial/ethnic minorities and sexual minorities) experience additional stressors (e.g., victimization and discrimination) due to being embedded in discriminatory societies (Meyer, 2003). Research with racial/ethnic minority groups indicates that every day discrimination (i.e., microaggressions) impacts both sleep duration and increased issues with sleep disturbance (Slopen et al., 2016). However, very few studies have examined the way minority stress may impact sleep with sexual minority men. To date, a study in France has identified how general stress is associated with poorer sleep for sexual minority men (Mountcastle et al., 2018) and a study in China identified that discrimination is associated with worse sleep quality for sexual minorities (Chan & Fung, 2021). As research in this area expands, the relationship between discrimination and sleep needs further exploration, especially to determine the mechanism by which discrimination impacts sleep quality.
Focusing on protective factors, resilience and thriving to reduce health disparities and treatment inequities
Published in The American Journal of Drug and Alcohol Abuse, 2022
Craig Field, Jennifer Reingle Gonzalez
One way of propelling research on health disparities and treatment inequities further is by adopting an overarching theoretical framework, particularly one incorporating biological markers. In this special issue, Hicks et al. (3) relied on the National Institute on Minority Health and Health Disparities’ research framework, which offers an interdisciplinary perspective integrating key biopsychosocial factors contributing to health disparities and treatment inequities. McEwen (12) offered the concept of allostasis and allostatic load as a comprehensive biological framework for understanding the effects of cumulative stress on health behavior and health outcomes. More recently, Epel and colleagues (13) extended this biological model of cumulative stress with a stress typology for the measurement of psychological stress. These models of cumulative stress have been implicated in both substance use disorders and health disparities (14,15) and, thus, may form the foundation for a common theoretical framework to guide health disparities research.