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Heartburn/Acid Reflux/Indigestion/Dyspepsia/Pyrosis/GERD
Published in Charles Theisler, Adjuvant Medical Care, 2023
Magnesium: Magnesium is a widely accepted and effective approach to treat dyspepsia or indigestion and taking it by mouth as an antacid reduces the burning symptoms.13 Various magnesium compounds can be used, but magnesium hydroxide (e.g., Milk of Magnesia 311 mg taking 2–4 chewable tablets every four hours up to four times per day)14 appears to work the fastest. A liquid form is also available. Taking 800 mg of magnesium oxide daily may also be beneficial.15
Basics of magnesium biodegradation
Published in Yoshinobu Onuma, Patrick W.J.C. Serruys, Bioresorbable Scaffolds, 2017
Michael Haude, Daniel Lootz, Hubertus Degen, Matthias Epple
Magnesium is an essential nutrient for humans, animals, and plants. Magnesium salts, which make up to 17% of sea salt, are released to the atmosphere as sea spray. The general population is exposed to magnesium compounds via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with compounds and consumer products containing magnesium compounds.
Commonly prescribed drugs
Published in Alistair Burns, Michael A Horan, John E Clague, Gillian McLean, Geriatric Medicine for Old-Age Psychiatrists, 2005
Alistair Burns, Michael A Horan, John E Clague, Gillian McLean
Antacids usually contain aluminium or magnesium compounds, and may cause improvement in symptoms in dyspepsia and gastro-oesophageal reflux (in the absence of erosions), where symptoms are expected to arise between me�is and at bedtime. Doses are 10 mi three or four times a day, and liquid preparations are more effective than solid. Magnesium-contain- ing antacids tend to be more laxative, and aluminium-containing ones tend to be more constipating. Sodium bicarbonate should no longer be used for the relief of dyspepsia, or bismuth-containing antacids because of the absorption of bismuth, which can be neurotoxic. An antifoaming agent, simethicone, can be added to relieve flatulence.
Elevation of brain magnesium with Swiss chard and buckwheat extracts in an animal model of reduced magnesium dietary intake
Published in Nutritional Neuroscience, 2022
Bassem F. El-Khodor, Karma James, Qing Chang, Wei Zhang, Yvette R. Loiselle, Chinmayee Panda, Taleen Hanania
Data from Figure 2 were calculated and presented in Figure 3 as a percentage of baseline level and provide visual comparison to [Mg2+]CSF data reported by Slutsky et. al. (2010) [2]. At day 15, [Mg2+]CSF was 9.5 and 8.3% higher than baseline for MgD + SC/BW extract and Mg threonate groups, respectively (p < 0.05) (Figure 3). In agreement with previous published work [2], repeated CSF sampling in rats that did not receive any magnesium supplementation (the two control groups) resulted in a 5-7% decrease in [Mg2+]CSF by the second sampling point (day 15). Taking into account this reduction in [Mg2+]CSF associated with repeated CSF collection (about 5%), the actual increase in [Mg2+]CSF with SC/BW extract and Mg threonate should be around 14.5 and 13.3%, respectively. Other magnesium compounds tested showed only marginal elevation of [Mg2+]CSF in comparison to vehicle controls (Figure 3).
Hypomagnesemia and hypermagnesemia
Published in Acta Clinica Belgica, 2019
The evidence to support one magnesium preparation over another is scarce and bio-availability or gastro-intestinal tolerance of many preparations is heterogeneous. Some studies in small study populations suggest a higher bioavailability of organic magnesium compounds while other studies demonstrated increased efficacy of supplements by intake during meals and/or preferably not during one single intake [11]. Magnesium oxide is reported to have the lowest bio-availability (4%) of all available supplements. Effects of food intake on bioavailability might play a role. High concentrations of minerals such as calcium in the intestine can decrease intestinal magnesium absorption which is also further impaired by partly or non-fermentable fibers, phytate and oxalate while absorption increases with concomitant intake of proteins, medium-chain triglycerides and low- or non-digestible carbohydrates which decrease the pH of the intestinal lumen increasing the solubility of minerals such as magnesium [11].
Management of pain using magnesium sulphate: a narrative review
Published in Postgraduate Medicine, 2022
Hassan Soleimanpour, Farnad Imani, Sanam Dolati, Maryam Soleimanpour, Kavous Shahsavarinia
Oral magnesium compounds are employed to hinder migraine. Magnesium supplementation has considerably improved the mean serum magnesium level and brought about pain relief in migraine patients [28]. Intravenous magnesium administration is also suggested as a curing option for migraines. Both ketorolac (30 mg) and magnesium sulfate (1 g) were considerably effective in migraine pain management; nevertheless, magnesium sulfate demonstrated higher effectiveness than ketorolac [29]. Moreover, 600 mg/day of magnesium is recommended as a safe and reasonable curing option for migraine care, which can increase to 1200 mg, if resisted [30].