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Natural Products from the Amazon Region as Potential Antimicrobials
Published in Mahendra Rai, Chistiane M. Feitosa, Eco-Friendly Biobased Products Used in Microbial Diseases, 2022
Josiane E. A. Silva, Iasmin L. D. Paranatinga, Elaine C. P. Oliveira, Silvia K. S. Escher, Ananda S. Antonio, Leandro S. Nascimento, Patricia P. Orlandi, Valdir F. Veiga-Júnior
Sesquiterpene is a chemical class comprising more than 300 compounds. They are terpenoids with skeletons containing 15 carbons, built from three isoprene units. Within this class there are several types of chemical structures, from linear to acyclic and cyclic carbon chains. The diversity of structures arises from the several biosynthetic forms in which sesquiterpenes can be produced and also by the diversity of possible chiral centers and stereospecific regions.
Medicinal Plants of Mongolia
Published in Raymond Cooper, Jeffrey John Deakin, Natural Products of Silk Road Plants, 2020
Narantuya Samdan, Odonchimeg Batsukh
Bioactivities: Hemostatic, antitumor, and antibacterial properties (Modonova et al., 1986). Cinaropicrin, apigenin, and apigenin-7-O-glycoside exhibit choleretic effects (Daariimaa, 2006; Glasl et al., 2007). Sesquiterpenes (Konovalova et al., 1979) were found to exhibit neoplasm-inhibiting and bactericidal activities (Modonova et al., 1986).
Natural Variability of Essential Oil Components
Published in K. Hüsnü Can Başer, Gerhard Buchbauer, Handbook of Essential Oils, 2020
The well-known caraway (Carum carvi) seems to be an essential oil–bearing species of relatively low variability concerning the oil constituents. Nowadays, besides being a popular spice, it is a source of essential oil of excellent antimicrobial properties, but the spasmolytic and cholagogue effects justify its use in phytotherapy, too. In the oil of caraway, the ratio of the main components S(+) carvone and R(+) limonene in the oil is above 90%, most frequently above 95% (Table 4.1). Variability is manifested in most cases only in their proportions compared to each other. Minor constituents have been rarely identified and mentioned. The majority of constituents are all monoterpenes, besides the sesquiterpene β-caryophyllene and some phenolic and aliphatic compounds.
GC-MS metabolites profiling of anethole-rich oils by different extraction techniques: antioxidant, cytotoxicity and in-silico enzymes inhibitory insights
Published in Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Dina M. El-Kersh, Nada M. Mostafa, Shaimaa Fayez, Tarfah Al-Warhi, Mohammed A. S. Abourehab, Wagdy M. Eldehna, Mohamed A. Salem
In anise EO prepared by solvent extraction (SE), microwave-assisted extraction (MAE) and hydro-distillation (HD) techniques, other classes were predicated mainly on sesquiterpenes class viz. sesquiterpenes hydrocarbons (6.47, 5.06 and 8.80%, respectively) and oxygenated sesquiterpenes (2.87, 0.19 and 0.75%, respectively) in addition to hydrocarbons detected only in solvent extraction method (2.30%). In star anise EO prepared by SE, MAE and HD, the other classes identified were predominantly monoterpenes as monoterpene hydrocarbons (0.95, 1.09, 3.69%, respectively) and oxygenated monoterpenes (0.62, 1.68, 1.28%, respectively). The detected chemical classes and their relative percentages are simplified in Figure 2. All volatiles identified in both anise and star anise EO were summarised in Table 1.
In vitro neuroprotective effects of farnesene sesquiterpene on alzheimer’s disease model of differentiated neuroblastoma cell line
Published in International Journal of Neuroscience, 2021
Mehmet Enes Arslan, Hasan Türkez, Adil Mardinoğlu
Sesquiterpene lactones (SL) are defined in a variety of plant families such as Acanthaceae, Anacardiaceae, Apiaceae, Euphorbiaceae, Lauraceae, Magnoliaceae, Menispermaceae, Rutaceae, Winteraceae, and Hepatideae and also include a variety of biologically active plant chemicals such as farnesene with a wide range of biological effects [15]. Sesquiterpene lactones are a class of naturally occurring plant terpenoids, which represent the diversity and unique class of natural products. They are important components of volatile oils formed from oxidative transformation to produce from head-tail condensation of three isoprene units from cyclization [16]. Sesquiterpenes, a member of the terpene family, have great importance due to their biological activity and their impact on human diseases. When the literature is reviewed, it has been determined that sesquiterpenes have a significant biological effect in wide spectrum researches. Sesquiterpenoids and especially Asteraceae sesquiterpene lactones have played important roles in human health as part of a balanced diet and as a pharmaceutical agent for their therapeutic potential for the treatment of cardiovascular diseases and cancer [17].
Volatile, non-volatile composition and insecticidal activity of Eupatorium adenophorum Spreng against diamondback moth, Plutella xylostella (L.), and aphid, Aphis craccivora Koch
Published in Toxin Reviews, 2019
Olonisakin Adebisi, Shudh Kirti Dolma, Praveen Kumar Verma, Bikram Singh, S. G. Eswara Reddy
The hydro distillation of the fresh aerial parts of plant yielded 0.06% (v/w), clear light yellow oil with a characteristic odor. Analysis of the oil led to the identification of 23 constituents, which represents 78.05% of the total oil as shown in Table 1. Among them, eighteen were hydrocarbons (60.50%) and five were oxygenated derivatives (39.50%). Sesquiterpenes were predominant (60%) while monoterpenes represented about 40% of the total amount. The main constituents of the sesquiterpenoid hydrocarbon present were β-bisabolene (3.38%), murolene (2.83%), β-farnesene (2.09%), and oxygenated derivatives were α-epi-cadinenol (16.63%), and α-bisabolol (4.08%). For monoterpenoid hydrocarbons the most abundant constituents are O-cymene (13.54%), α-phyllandrene (7.46%), 2-σ-carene (5.77%), and camphene (3.59%) with bornyl acetate as oxygenated derivative of mono terpenoid.