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Prevention of Microbial Contamination during Manufacturing
Published in Philip A. Geis, Cosmetic Microbiology, 2020
Peroxy-hydrogen peroxide compounds such as peroxyacetic acid and peracetic acid can be used as sanitizers. Peracetic acid is a mixture of acetic acid and hydrogen peroxide. When dissolved in water, peracetic acid disintegrates into hydrogen peroxide and acetic acid which will eventually degrade into water, oxygen and carbon dioxide. Peracetic acid is considered to be a more potent sanitizer than hydrogen peroxide (75). The advantages of using peroxy-hydrogen peroxide compounds are that they have bactericidal, fungicidal and sporicidal activity, are non-corrosive to stainless steel and aluminum, are tolerant to organic soil and break down into acetic acid and water. The disadvantages are that they are corrosive to soft metals (iron, copper, zinc, brass, galvanized steel, etc.), have a pungent odor and their antimicrobial activity will vary against different fungal species.
Ecology
Published in Paul Pumpens, Single-Stranded RNA Phages, 2020
The MS2 aggregation effect was studied by the phage inactivation with peracetic acid and the latter was recommended for the treatment of water containing viral aggregates (Mattle et al. 2011). The exposure of the phage MS2 that was deposited on different test materials to different formulations of a solid source of peracetic acid was studied by Buhr et al. (2014).
Assessment and Examination of the Larynx
Published in John C Watkinson, Raymond W Clarke, Terry M Jones, Vinidh Paleri, Nicholas White, Tim Woolford, Head & Neck Surgery Plastic Surgery, 2018
Jean-Pierre Jeannon, Enyinnaya Ofo
Cleaning may be manual or mechanical but must remove all visible debris. It is no longer recommended to use gluteraldehyde for chemical high-level disinfection owing to its toxicity38–40 and ability to fix proteins onto the endoscope surfaces, making their subsequent removal more difficult.35 Suitable options for chemical disinfection include electrolyzed saline (Sterilox®); chlorine dioxide (Tristel®); peracetic acid (Steris®, Nucidex®, Perasafe®, Gigasept®). Peracetic acid is irritant to skin and the respiratory system.34 Tristel is used by many ENT clinics in the UK.34, 41
Natural compounds and extracts as novel antimicrobial agents
Published in Expert Opinion on Therapeutic Patents, 2020
Paolo Guglielmi, Virginia Pontecorvi, Giulia Rotondi
Essential oils, along with other plant-derived extracts or compounds and an emulsifier were the constituents of embodiments with antimicrobial activity [36]. In particular, the patent reports a series of compositions including one or more essential oils, plant extracts and/or plant derived compounds, along with one or more emulsifier (the latter being able to increase or maintain suspension or dispersion of one liquid in another such as for example a mixture of an oil and water). Furthermore, ozone or other additional sanitizers like peracetic acid, lactic acid etc., can be present in the composition, thus enforcing the antimicrobial activity. Ozone can be generated using an ozone generator and introduced in a solution using a sparger. In Table 8 are reported the essential oils, plant-derived compounds, plant extracts and emulsifiers, ozone and other sanitizers employed in the compositions along with the concentrations of the various substances.
Microbiological monitoring of ultrapure dialysis fluid in a hemodialysis center in Alexandria, Egypt
Published in Alexandria Journal of Medicine, 2018
Aleya A. Abbass, Ahmed F. El-Koraie, Walaa A. Hazzah, Eman A. Omran, Mohammed A. Mahgoub
This cross-sectional study was carried out during a 6-months period, on a total of 100 dialysis fluid samples randomly collected from a private HD center in Alexandria, Egypt. The HD unit consists of one water treatment unit and two rooms for HD. In this unit, water passes through a RO filter and a mixed bed DI, and then it is stored in a tank of 1000 Liter capacity. The finally treated water is pumped into two rooms of HD through a system of polyvinyl chloride (PVC) pipes to reach every HD machine. Chlorination is done every month for maintenance of water treatment unit and the bacterial filter (0.2 µm) is substituted every month. The total number of HD machines in both HD rooms is eight machines. The first room is back to back to the water treatment unit and contains three machines. On the other hand, there is a long distance (about 20 m) between the water treatment unit and the second room which contains five machines. Most of the machines were commercial type A, the remaining were type B which is relatively newer version with some technological advances. The dialysate concentrate used in this unit is a sealed sterile capsulated bicarbonate powder along with the complementary solution A for bicarbonate based HD (referred to as A-component). Chemical disinfection of machines is done after every session using 0.2% peracetic acid solution 30 min at room temperature.
Candidemia in the cancer patient: diagnosis, treatment, and future directions
Published in Expert Review of Anti-infective Therapy, 2018
Matthew W. McCarthy, Thomas J. Walsh
These non-albicans species now also include C. auris, which was first identified in Japan in 2009 and has since spread throughout the work and has been associated with nosocomial transmission and multidrug resistance and may also pose a threat to patients with malignancy [56]. The ability of this organism to withstand environmental stressors creates a challenge for removing it from hospitals [57–59]. C. auris was shown to selectively tolerate clinically relevant concentrations of disinfectants such as sodium hypochlorite and peracetic acid, which may explain its ability to successfully persist within the hospital environment [60].