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Fungi and Water
Published in Chuong Pham-Huy, Bruno Pham Huy, Food and Lifestyle in Health and Disease, 2022
Chuong Pham-Huy, Bruno Pham Huy
Some medicinal mushrooms include Lingzhi or Reishi, Yun zhi or Trametes (Coriolus) versicolor and Cordyceps sinensis. They are used in Asian traditional medicine and are the subjects of much modern academic research.
Potential of Mycochemicals in the Prevention and Control of Microbial Diseases
Published in Mahendra Rai, Chistiane M. Feitosa, Eco-Friendly Biobased Products Used in Microbial Diseases, 2022
Over the years, etiological agents responsible for microbial diseases have developed resistance against common microbiostatic and microbiocidal agents used in preventing and controlling them. Microorganisms have developed various mechanisms to evade or neutralize the effects of these antimicrobial agents. Therefore, there is a renewed interest to search for safe and more effective microbiostatic and microbiocidal agents. Edible and medicinal mushrooms are known to be source of safe and effective bioactive agents that can be used to check the negative activities of microorganisms responsible for microbial diseases. Mushrooms can be cultivated on cellulosic waste from which they can acquire various bioactive compounds. The growth medium can also be spiced with various mineral elements that can enhance the effectiveness of the bioactive compound as an antimicrobial agent.
Medicinal Mushrooms
Published in Anil K. Sharma, Raj K. Keservani, Surya Prakash Gautam, Herbal Product Development, 2020
Temitope A. Oyedepo, Adetoun E. Morakinyo
Medicinal mushrooms have been in use as medicine and food nutrient for many years because of their remarkable bioactivities. There are myriads of edible and nonedible mushrooms with established physiological activities. Medicinal mushrooms are therefore generating a lot of attention as potential natural agents for the prevention and treatment of many diseases. Bioactive compounds from a good number of these medicinal mushrooms have been identified, extracted and prepared in the form of nutraceuticals and dietary supplement.
Morel mushroom, Morchella from Kashmir Himalaya: a potential source of therapeutically useful bioactives that possess free radical scavenging, anti-inflammatory, and arthritic edema-inhibiting activities
Published in Drug and Chemical Toxicology, 2022
Haridas Ramya, Korattuvalappil S. Ravikumar, Zuhara Fathimathu, Kainoor K. Janardhanan, Thekkuttuparambil A. Ajith, Manzoor Ahmad Shah, Ramona Farooq, Zafar A. Reshi
The existence of free radicals and their relevance in pathophysiology of diseases are extensively investigated in recent years. Under normal conditions, healthy body has a balance between free radical and antioxidant defense. When this balance is disturbed, the condition leads to oxidative stress. Oxidative stress can cause injury to biomolecules resulting into numerous ailments including cancer and cardiovascular diseases. Reactive oxygen species (ROS) and increased levels of blood lipid are key to the pathogenesis of atherosclerosis, one of the major cause of mortality in recent years. Antioxidants are major defense against radical-mediated toxicity by protecting damages caused by free radicals and ROS. Protection of biomolecules from ROS-mediated damage by natural products is considered to be promising. Phenolics and flavonoids contents of natural products contribute to the antioxidant activity. Several edible and medicinal mushrooms have been reported to possess significant antioxidant activity (Ajith and Janardhanan 2007). The result of the current experimental studies reveal that morel mushroom, M. elata from Kashmir Himalaya possessed profound free radical scavenging activity. The various solvent extract of this mushroom showed marked DPPH, ABTS, hydroxyl, nitric oxide scavenging, and lipid peroxide-inhibiting activities in vitro.
Anticancer Characteristics of Fomitopsis pinicola Extract in a Xenograft Mouse Model—a Preliminary Study
Published in Nutrition and Cancer, 2020
Chi H. J. Kao, David R. Greenwood, Stephen M. F. Jamieson, Margaret E. Coe, Pamela M. Murray, Lynnette R. Ferguson, Karen S. Bishop
Although medicinal mushrooms have been used by various cultures for centuries, they have only relatively recently been investigated for their application in modern medicine. Medicinal mushrooms have been used as an adjuvant to cancer therapy by alleviating the side-effects of chemo- and radiation therapy such as nausea, anemia, and a lowered immune system (4). Furthermore, numerous clinical trials have been conducted to assess the potential anticancer properties of commercially prepared medicinal mushrooms (4).
In vitro Anti-colorectal Cancer Potential of the Medicinal Mushroom Ganoderma neo-japonicum Imazeki in Hyperglycemic Condition: Impact on Oxidative Stress, Cell Cycle and Apoptosis
Published in Nutrition and Cancer, 2022
Meng-Fei Lau, Kek-Heng Chua, Vikineswary Sabaratnam, Umah Rani Kuppusamy
Medicinal mushrooms exert myriad biological activities on tumor progression (22), but the influence of glucose in modulating their anticancer capacities is still a matter of speculation. This study is the first to compare the cytotoxicity of G. neo-japonicum under euglycemic and hyperglycemic conditions using CRC models.