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Evidence-Based Medicine and Resource Allocation
Published in Rui Nunes, Healthcare as a Universal Human Right, 2022
Access to pharmaceuticals as well as the overall healthcare policy is grounded in an accepted right to healthcare access, notwithstanding the fact that priorities must be set even in the access to useful medicines. Further, in a global environment of health research, health biotechnology will challenge the ethical limits of any healthcare system at the national and global levels (Zhenzhen et al. 2004). Indeed, any healthcare system will face the pressure of emerging technologies, which must be carefully evaluated both in publicly financed systems and in more liberal ones (Kaebnick and Gusmano 2018). Precision medicine is a good example of this.
Bio-Implants Derived from Biocompatible and Biodegradable Biopolymeric Materials
Published in P. Mereena Luke, K. R. Dhanya, Didier Rouxel, Nandakumar Kalarikkal, Sabu Thomas, Advanced Studies in Experimental and Clinical Medicine, 2021
It is a saying that when you are evaluating the present situations and predicting the future, one must also reconsider the past. The modern medical field has begun to understand, realize, and utilize the benefits of biotechnology in health care similar to all other sectors. Design and material concepts for surgical implants are a study of material sciences and biomechanical sciences. Implants are being considered as a first treatment option by patients as it is so popular amongst over the other treatment modalities. It became o the mainstream for a dental practice. It has grown greater still a long way to achieve in the field of bio-implants. The process and investigation of biological component show that polymer material can be the best material which equally acts and reacts with better characteristics of biomaterials. It has good mechanical properties and can be used for the feature implants.
Introduction to Vaccination
Published in Mesut Karahan, Synthetic Peptide Vaccine Models, 2021
Nezih Pişkinpaşa, Ömer Faruk Karasakal
Recently, new and advanced molecular biology and biotechnological methods have been used in obtaining vaccines with fewer side effects. Drugs created with biotechnology have some disadvantages due to factors such as the need for advanced laboratories, advanced devices, high cost, and experienced personnel. However, biotechnological vaccines only have a sequence encoding the antigenicity portion. The DNA encoding the antigen is isolated and integrated into the cells that do not have the disease-specificity and the desired protein is synthesized. Biotechnological vaccines do not form an infection and turn out to eliminate the disadvantages of classical vaccines (Mzula et al. 2019).
Screening of interleukin 17F gene polymorphisms and eight subgingival pathogens in chronic periodontitis in Libyan patients
Published in Libyan Journal of Medicine, 2023
Eshraq Alsherif, Inas Alhudiri, Mouna ElJilani, Ahmad Ramadan, Paul Rutland, Adam Elzagheid, Nabil Enattah
This case-control study consisted of 100 Libyan adults (50 females and 50 male). Fifty healthy controls (HC) and 50 CP patients whose ages ranged between 25 - 65 years were included. Libyan adults were randomly selected from volunteers who live in different geographical places in Libya, divided into three geographic regions (West, East, and South). Patients enrolled signed an informed consent form. Ethical approval for this study was obtained from the Bioethics Committee at Biotechnology Research Center (BEC.BTRC0 5–2018). Questionnaires in Appendix 1 and 2 were filled, and oral examinations carried out in the Periodontology Department of Faculty of Dentistry, University of Tripoli, in addition to other public and private dental clinics, the study was conducted in the laboratories of Genetic Engineering Department at Libyan Biotechnology Research Center in Tripoli-Libya.
Novel formulations of metal-organic frameworks for controlled drug delivery
Published in Expert Opinion on Drug Delivery, 2022
Congying Rao, Donghui Liao, Ying Pan, Yuyu Zhong, Wenfeng Zhang, Qin Ouyang, Alireza Nezamzadeh-Ejhieh, Jianqiang Liu
Both protein’s surface charge and chemical properties decide whether itself could be encapsulated into MOFs or not [102]. Up to date, the numbers of research on studies of encapsulating proteins into MOFs and summaries of the encapsulation strategies remain small. Chen et al. first reported a general surface-charge-independent approach (amino acid enhanced a pot buried (AAOPE)) for producing MOF-encapsulated proteins (Figure 6) [103]. The accelerated formation of prenucleation clusters around proteins is the critical success of the process. The successful encapsulation of 12 proteins, including enzymes, etc., with various surface chemical properties into ZIF-8 has been reported in later researches. The process is independent of the proteins’ surface charge. Further, a simple pH modification can easily reach the controllable release of encapsulant by this nondestructive process. These prove potent biotechnology applications of the process.
Can Moral Enhancement Address Our Environmental Crisis? A Call for Collective Virtue-Oriented Action
Published in AJOB Neuroscience, 2021
Brooke Burns, Nicolae Morar, Rebekah Sinclair, Kirstin Waldkoenig
Proponents of moral enhancement present this biotechnology as a viable solution to social and political problems. The projected imperative to enhance ourselves morally is a direct response to our perceived moral unfitness (Persson and Savulescu 2012). Our present moral traits are seen as unable to adequately promote large-scale cooperation, which is necessary to appreciate the consequences of dangerous technological developments and to address current existential problems such as global climate change. Fabiano aims to provide a “safety framework” for the appropriate application of moral enhancement through the following requirements: practical robustness to moral uncertainty, empirical adequacy, balance between dispositions, preservation of identity, and sensitivity to practical considerations. Fabiano argues that virtue theory best attends to these desiderata and illuminates how the safety framework is to be adequately applied. When moral enhancement draws on virtue theory, an intervention can be made into the agent’s moral behaviors and character traits, so that they can actually achieve the good (Fabiano 2021).