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Synovitis in hemophilia: preventing, detecting, and treating joint bleeds
Published in Expert Review of Hematology, 2023
E. Carlos Rodriguez-Merchan
Occasionally, treatment of synovitis requires pain alleviation. Furthermore, some approaches to pain management also reduce inflammation and ameliorates synovitis. Multimodal pain treatment, including multimodal analgesia, PRM, and psychological therapies (imagery or relaxation, hypnosis), is the most recommended approach for patients with hemophilia. Paracetamol/acetaminophen should be recommended if the pain is mild, metamizole if the pain is moderate, and soft opioids (codeine or tramadol) if the pain is severe. Sometimes COX-2 inhibitors, intra-articular injections of hyaluronic acid, and behavioral therapies are required [41,42]. Post-synoviorthesis rehabilitation is paramount to reducing the risk of fibrous ankylosis of the joint [39].