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Paper 3
Published in Amanda Rabone, Benedict Thomson, Nicky Dineen, Vincent Helyar, Aidan Shaw, The Final FRCR, 2020
Amanda Rabone, Benedict Thomson, Nicky Dineen, Vincent Helyar, Aidan Shaw
In primary synovial chondromatosis there is proliferation of the synovium which can cause intra-articular loose bodies; these may or may not calcify. Imaging features in this condition can include soft tissue swelling around the joint and widening of the joint space as well as erosion of the adjacent bone. Multiple calcific densities may be present in the joint space, which are uniform in size.
Arthroscopic hip preservation surgery
Published in K. Mohan Iyer, Hip Preservation Techniques, 2019
Synovial chondromatosis and loose bodies can be managed arthroscopically; studies have observed that some patients recovered well without the need for further treatments. Due to difficulties in accessing posteromedial and posterolateral areas in the peripheral compartment, recurrences can be higher.
Benign tumors
Published in Archana Singal, Shekhar Neema, Piyush Kumar, Nail Disorders, 2019
Extraskeletal or soft tissue chondroma is thought to derive from the connective tissue, not preexisting chondrocytes.226 Clinically, it mimics parosteal chondroma. The clinical differential diagnosis comprises a number of other chondromatoses that rarely affect the digits, such as synovial chondromatosis. Histopathologically, all chondromas are characterized by a proliferation of hyaline cartilage irregularly arranged cells, but without mitoses or cellular atypias. In the differential diagnosis, chondroblastoma and chondrosarcoma are important.
The role of imaging in juvenile idiopathic arthritis
Published in Expert Review of Clinical Immunology, 2018
Clara Malattia, Mariangela Rinaldi, Alberto Martini
Over the last decade, evidence has revealed that delays in diagnosis and treatment of chronic inflammatory arthritides might reduce the chance of remission and cause unnecessary disease progression [3]. Increasing emphasis has thus been placed on the identification of patients at the earliest stages of the disease. The 2010 American College of Rheumatology (ACR)/EULAR classification criteria have included imaging modalities such as MRI and MSUS to enable early diagnosis of RA patients [27]. Of note, the combination of synovitis and BME, as revealed by wrist MRI, significantly increases the diagnosis of RA from undifferentiated arthritis [28]. So far, no study has specifically addressed the role of MRI in diagnosis of JIA. In addition, wrist MRIs of a large Norwegian cohort of healthy children have shown that BME is present in up to 50% of healthy controls, thus limiting the specificity of this finding to diagnose JIA [6]. Despite that, the role of MRI remains unquestionable to rule out other synovial pathologies that could mimic JIA, such as pigmented villonodular synovitis, hemangioma, synovial chondromatosis, or lipoma arborescens [4,16].
Synovial chondromatosis of the distal radio-ulnar joint
Published in Baylor University Medical Center Proceedings, 2021
David Botros, Ken Ford, Brendan Holderread, Al Mollabashy, James Rizkalla
Synovial chondromatosis (SC) is a benign metaplastic proliferation of cartilaginous nodules within the synovial membrane, often presenting with classically described “loose bodies” occupying the joint space.1,2 SC occurs in approximately 1.8 per 1 million individuals.3 Though in theory any articular space is at risk of SC, the literature suggests a predilection to the knee and hip, with nearly 90% of all cases of SC occurring at these sites.4 This article describes an incredibly rare case of SC of the distal radio-ulnar joint (DRUJ) that was more aggressive than described in previous case reports. The aggressiveness and local recurrence of this lesion ultimately required amputation as the definitive treatment.
Biologic therapies for foot and ankle injuries
Published in Expert Opinion on Biological Therapy, 2021
MaCalus V. Hogan, Devon M. Scott, Stephen P. Canton, Dukens LaBaze, Alan Y. Yan, James H-C. Wang
A benign tumor of the synovial membrane, synovial chondromatosis, generated interest among researchers to investigate its use in cartilage regeneration. In vitro, these cells demonstrate high chondrocyte potential than the more common MSC sources. Periosteum-derived stem cells are very novel but have chondroprogenitor cells and dual lineage (bone and hyaline cartilage) potential.