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Diabetic Retinopathy
Published in Jahangir Moini, Matthew Adams, Anthony LoGalbo, Complications of Diabetes Mellitus, 2022
Jahangir Moini, Matthew Adams, Anthony LoGalbo
Diffuse macular edema involves retinal capillary leakage over wide areas and a large amount of breakdown of the blood-retinal barrier. Cystoid fluid often accumulates in the perifoveal macula, known as cystoid macular edema. Criteria have also been developed that help determine the clinical significance of either type of macular edema, influencing treatments.
Use of Electronic Health Records, Disease Registries, and Health Insurance Databases in Ophthalmology
Published in Ching-Yu Cheng, Tien Yin Wong, Ophthalmic Epidemiology, 2022
Rachel Marjorie Wei Wen Tseng, Grace May Chuang, Zhi Da Soh, Yih-Chung Tham
The SNIIR-AM database in France started in 2003. However, the usage of this database in ophthalmology is relatively new, and the data have mainly been used for the Epidemiology and Safety (EPISAFE) program in cataract surgery. Notable reports from this database included evaluation on incidence rates of cataract surgery between 2009 and 2012. It was observed that the incidence of cataract surgery increased from 9.86 to 11.08/1,000 person-years. The incidence of pseudophakic cystoid macular edema was 0.95%. On the other hand, from 2005 to 2014, based on data derived from more than 6 million cataract surgeries, the incidence of endophthalmitis post-cataract surgery was recorded to decrease from 0.15 to 0.05% (46).
Management of traumatic lens subluxation and dislocation
Published in A Peyman MD Gholam, A Meffert MD Stephen, D Conway MD FACS Mandi, Chiasson Trisha, Vitreoretinal Surgical Techniques, 2019
Some patients may develop epiretinal membranes, especially if the posterior hyaloid face was not removed at the time of surgery. These also can greatly contribute to persistent cystoid macular edema postoperatively. These membranes are subsequently removed when they become visually significant.
A Comparative Study between Occlusive and Non-occlusive Retinal Vasculitis: Data from a Referral Center in Tunisia, North Africa
Published in Ocular Immunology and Inflammation, 2023
Nesrine Abroug, Molka Khairallah, Imen Ksiaa, Hager Ben Amor, Sourour Zina, Sonia Attia, Bechir Jelliti, Sana Khochtali, Moncef Khairallah
Previous studies showed that cystoid macular edema and macular ischemia are associated with worse visual outcome.4,10,22 In addition, Maleki et al. found that lower BCVA was significant independent risk factors for poor visual outcome in patients with idiopathic RV.4 Our results are partly consistent with this study. In our cohort, we did show that worse visual acuity at baseline visit was 6.68 and 23.13 times more likely to cause poor visual outcome in both occlusive and non-occlusive RV, respectively. We also found that development of optic atrophy independently predicted a poor visual outcome in eyes with ORV which is consistent with the recent report by Lin et al.22 In addition, retinal hemorrhages were significant independent risk factor of poor visual outcome in the ORV group. In fact, extensive deep intraretinal hemorrhages in the setting of uveitis are a hallmark of severe occlusive RV with diffuse non-perfusion. In such case, early aggressive systemic anti-inflammatory therapy may prevent sight-threatening complications.
The Role of Screening for Asymptomatic Ocular Inflammation in Sarcoidosis
Published in Ocular Immunology and Inflammation, 2022
Jennifer Lee, Fatma Zaguia, Caroline Minkus, Anjum F. Koreishi, Andrea D. Birnbaum, Debra A. Goldstein
Our data do not support the routine screening of sarcoidosis patients for uveitis in the absence of ocular symptoms. This is in stark contrast to juvenile idiopathic arthritis (JIA)-related uveitis, where screening ophthalmic examinations are required, as the disease tends to be asymptomatic. Recent updates from the rheumatology literature have reported a cumulative incidence of uveitis of up to 12.9% in the first five years of disease in children with JIA, where the majority of patients are asymptomatic at presentation.18 Furthermore, young JIA patients do not often report symptoms even if their visual acuity loss is advanced, with up to 24% of patients presenting with a visual acuity of 20/200 or less due to ocular complications such as cataract, central band keratopathy or glaucoma.19 In contrast, sarcoidosis-associated uveitis tends to have a more favorable visual prognosis. In a retrospective study of 83 patients, only 9 patients (11%) had poor visual outcomes (visual acuity ≤ 20/50) largely due to cystoid macular edema (8 patients, 89%, p = .009).20
Chronic Unilateral Uveitis as a Manifestation of Leprosy: A Case Report and Literature Review
Published in Ocular Immunology and Inflammation, 2021
Claudia Eugenia Duran Merino, María Camila Ortiz Úsuga, María Jaramillo Jaramillo, Ana María Rodríguez
As in unusual pathologies, differential diagnosis should be considered including Fuchs heterochromic iridocyclitis, which was the initial diagnosis in this case, and viral uveitis.29 Fuchs uveitic syndrome, as mentioned in the literature, is characteristically monocular associated with central and stellar keratic precipitates. In the iris, anterior stromal atrophy can be found, it is also seen in the infection caused by leprae, although in Hansen´s disease seems to be deeper. It is infrequent to find posterior compromise as cystoid macular edema, usually, patients with Fuchs iridocyclitis are not very symptomatic or present with significant decreased vision, but present with cataract or glaucoma.30 Our patient, although with monocular symptoms, had severe decreased vision and associated cystoid macular edema. In viral uveitis, the course is usually self-limited and is associated with the systemic infectious peak. Acute retinal necrosis caused by viruses of the Herpes family presents with severe and marked inflammatory symptoms associated with focal chorioretinal and vasculitic lesions.