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Tumors of the Nervous System
Published in Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, Joanna M. Wardlaw, Hankey's Clinical Neurology, 2020
Types of germ cell tumors include: Germinoma.Embryonal carcinoma.Yolk sac tumor.Choriocarcinoma.Mature teratoma.Immature teratoma.Mixed germ cell tumor.
Germ-Cell Cancer of the Testis and Related Neoplasms
Published in Pat Price, Karol Sikora, Treatment of Cancer, 2020
The use of PET CT in metastatic non-seminoma is contentious.50 Although active cancer will have PET uptake, necrotic tissue can contribute to a false-positive PET scan. Moreover, mature teratoma has either low or negligible uptake.
Knowledge Area 14: Gynaecological Oncology
Published in Rekha Wuntakal, Ziena Abdullah, Tony Hollingworth, Get Through MRCOG Part 1, 2020
Rekha Wuntakal, Ziena Abdullah, Tony Hollingworth
Macroscopically, they are large tumours up to 25 cm in size, predominantly solid with a capsule. Often there are areas of haemorrhage and necrosis. A mature teratoma may be present in the contralateral ovary in 10% of cases.
Umbilical Cord Teratoma – A Short Case Report
Published in Fetal and Pediatric Pathology, 2023
Manuela Enciu, Gabriela Izabela Baltatescu, Oana Cojocaru, Ionut Burlacu, Viorel Constantin Cristurean, Liliana Mocanu, Sinziana-Andra Ghitoi, Alexandra Dinu, Antonela-Anca Nicolau
Teratomas contain multipotent embryonic cells from the three germcell layers and are usually characterized by cystic structure, most often developing in the gonads. Extragonadal localization in the umbilical cord is one of the least encountered sites, with less than 20 reports in the literature [1,2]. Umbilical cord teratomas may be associated with several malformations or chromosomal anomalies and they can result in various fetal outcomes, from normal development term birth to in utero fetal demise with multiple malformations, and should prompt additional diagnostic studies in the fetus/newborn. The first case of umbilical cord teratoma was described by Budin et al. (1878) [4] as a tumor shaped like an “adult fist” in the umbilical cord of a new-born with slight cyanosis [3,4]. Additional studies document unfavorable outcomes to the pregnancies. In this paper, we report an extragonadal mature teratoma without other clinical consequences.
Late effects in patients with sacrococcygeal teratoma: A single center series
Published in Pediatric Hematology and Oncology, 2018
Salih Güler, Metin Demirkaya, Emin Balkan, İrfan Kırıştıoğlu, Nizamettin Kılıç, Betül Sevinir
The female/male ratio was 2.3. Median age of diagnosis of the patients was 22 days (1 day–14.6 years) and mean follow-up term was 78.5 ± 44 months (26–206 months). Of the patients (14/40) 35% were diagnosed during the antenatal period, (9/40) 22.5% in the neonatal period, (7/40) 17.5% between 1 and 12 months, (6/40) 15% between 13 and 24 months, and (4/40) 10% after 24 months. In 35 patients with a determined mass diameter, the largest mass diameter was between 2 and 30 cm. Mass was smaller than 10 cm in (24/35) 68.5% of patients and larger than 10 cm in (11/35) 31.4%. According to Altman classification, (9/40) 22.5% of the cases were type I, (10/40) 25% were type II, (15/40) 37.5% were type III, and (6/40) 15% were type IV. Histopathologically, (26/40) were mature teratoma, (4/40) 10% were immature teratome and (10/40) 25% were malignant teratoma. All the patients with malignant teratoma were older than 6 months (Table 1).
Immature teratoma of the uterine cervix
Published in Journal of Obstetrics and Gynaecology, 2022
Manizheh Sayyah-Melli, Behrouz Shokohi, Shabnam Yagoobi, Ali Adili, Seyyedeh Sanaz Hosseini
Teratomas usually arise in the gonads and mainly develop in midline structures; and, extragonadal types of teratomas are infrequent (Kurman et al. 2011). (Oosterhuis et al. 2007; Misra et al. 2014). Cervical teratoma, is relatively rare (Oosterhuis et al. 2007). It is suggested that this type of tumour in the cervix and endometrium may be originated from residual foetal tissue. To our knowledge, there have been a few uterine cervical immature teratoma cases reported in the literature to date. In contrast to our case, which was presented with pelvic pressure, constipation and report of a leiomyoma behind the cervix, all reported cases had originated from the cervical canal with abnormal vaginal bleeding (AUB) (Cortes et al. 1990; Panesar and Sidhu 2007; Ito et al. 2019) (Cortes et al. 1990) (Panesar and Sidhu 2007), or the uterine fundus (Iwanaga et al. 1993; Gomez-Lobo and Burch 2008; Souza et al. 2014). In this case, the patient had no AUB. Another case reported by F Khorsandi showed a solid tumour of the left corner of the external os (Khorsandi and Anabitarte 1981). In contrast to the study of Simona Stolnicu and colleagues, in which immature solid teratomas involved uterine corpus, ovary and mature teratomas, the cervix and para-uterine tissue, in our study, the ovaries looked normal (Stolnicu et al. 2017). There was also differences between our study and the study of Zamani et al. In this study, the authors reported a necrotised mature teratoma of the uterus with aggressive behaviour (Zamani et al. 2018). In contrast, our case originated from the posterior surface of the cervix progressed to the recto-uterine pouch, parametrium and pelvic sidewall.