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Microneedling
Published in Rubina Alves, Ramon Grimalt, Techniques in the Evaluation and Management of Hair Diseases, 2021
Rachita S. Dhurat, Sanober Burzin Daruwalla
Microneedling is a relatively new minimally invasive procedure involving superficial and controlled puncturing of the skin by rolling with miniature fine needles. Microneedle (MN) could be a single or an array of micron-sized needles that can penetrate the epidermis and upper dermal layer of the skin. Microneedle-based technologies are used for various cosmetic, therapeutic, and diagnostic applications. Traditionally used as a collagen induction therapy for facial scars and skin rejuvenation, the scope of microneedling has expanded for hair stimulation and for transdermal delivery of therapeutic drugs and vaccines.
Microneedling in Clinical Practice
Published in Boris Stoeber, Raja K Sivamani, Howard I. Maibach, Microneedling in Clinical Practice, 2020
Aunna Pourang, Kourosh Beroukhim
Microneedling induces minimal epidermal injury, mitigating the adverse effects seen with ablative therapies. In fact, re-epithelialization occurs within 24 hours and epidermal barrier function is, for the most part, maintained (19, 20). The main postulated mechanism by which microneedling confers most of its benefits is through collagen induction that occurs during the body's normal response to trauma and wound healing. For this reason, microneedling is often referred to as percutaneous collagen induction therapy.
Treatment Algorithm for Acne Scars
Published in Antonella Tosti, Maria Pia De Padova, Gabriella Fabbrocini, Kenneth R. Beer, Acne Scars, 2018
Daniele Innocenzi, Ilaria Proietti, Concetta Potenza, Patrick M. Zito, Kenneth R. Beer
The mechanism of action of the collagen induction therapy (CIT) is based on scientific facts that skin cells communicate by electrical signals. When the skin is microneedled, cells react to this intrusion by changing their internal electrical potential. This electrical charge in return stimulates skin cells to release chemical compositions, protein and growth factors. Proliferated skin cells, such as fibroblasts, migrate to the point of injury and transform into collagen fibers [69].
Efficacy of fractional carbon dioxide laser versus microneedling in the treatment of striae distensae
Published in Journal of Cosmetic and Laser Therapy, 2019
Mona Soliman, Mohamed Mohsen Soliman, Amira El-Tawdy, Hoda Sayed Shorbagy
Our study recorded 55% moderate to excellent improvement of striae after microneedling-treated side. We found 66.7% of patients were satisfied with this procedure. Same opinion was conducted by Aust and his colleagues when they performed microneedling technique on their patients with striae. They did one to four sessions with 4-week intervals and they proved that percutaneous collagen induction was simple and safe method to treat stretch marks and scars. Percutaneous collagen induction therapy was found very effective in reducing depressed scars by promoting neocollagenesis (7). Also Park et al performed needling therapy on 16 Korean cases with striae. The patients received 3 sessions with 4-week intervals. Their results showed that 43.8% of patients had marked to excellent improvement and they concluded that microneedling could be safely and effectively used in resolving striae (8).
Skin microneedling plus platelet-rich plasma versus skin microneedling alone in the treatment of atrophic post acne scars: a split face comparative study
Published in Journal of Dermatological Treatment, 2018
Mohamed Kotb Ibrahim, Shady Mahmoud Ibrahim, Amany Mohamed Salem
Microneedling is a relatively new minimally invasive procedure involving superficial and controlled puncturing of the skin by rolling with miniature fine needles to induce a normal wound healing process with release of several growth factors, including platelet-derived growth factor, fibroblast growth factor, and transforming growth factors α and β, which stimulate the migration and proliferation of fibroblasts (13). Another hypothesis has been also proved by Jaffe, 2007 (14) who mentioned that cell membranes react to the local change with an electrical potential that creates increased cell activity and the release of potassium ions, proteins and growth factors. Over a short period of time, it has gained mass popularity and acceptance as it is a simple, cheap, safe, and effective technique requiring minimal training. Traditionally used as a collagen induction therapy for facial scars and skin rejuvenation, it is also widely used now as a transdermal delivery system for therapeutic drugs and vaccines (15).
Delayed hypersensitivity reaction from microneedling twenty years after silicone fillers
Published in Orbit, 2023
Grace S. Ahn, Michelle Ting, Catherine Y. Liu, Bobby S. Korn, Don O. Kikkawa
Microneedling has been increasingly used to treat common conditions such as inflammatory acne and acne scarring,1 photodamaged skin,2 and even radiation dermatitis.3 In contrast with roller and automated devices, fractional radiofrequency microneedling (FRM) uses radiofrequency to induce neocollagenesis and is often performed alongside topical products applied immediately after in a procedure known as percutaneous collagen induction therapy (PCIT). However, appropriate clinical judgment is critical given the potentially dangerous consequences owing to deep penetration of the dermis.