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The Islamic Golden Age
Published in Scott M. Jackson, Skin Disease and the History of Dermatology, 2023
Avicenna's descriptions of bullous eruptions may be an early description of pemphigus, a severe blistering disease now known to be autoimmune in nature. To Avicenna, there are two types of blistering: bubbles and blisters.13 Bubbles are caused by the boiling of humors in the body which releases water and a thin part of the humor under the skin. These remain under the skin and do not contain pus. Blisters are caused by a thin blood substance released under the skin, which then putrifies, fills with pus, and inflates the skin.
Cold Sores/Herpes Simplex/Herpes Labialis
Published in Charles Theisler, Adjuvant Medical Care, 2023
Herpes labialis, also known as cold sores or fever blisters, is a common viral infection. The blisters are caused by the herpes simplex virus (HSV). Symptoms usually begin with a tingling or burning sensation on or near the lips. This is followed by the appearance of small, painful, fluid-filled blisters that are single or can be grouped together form on and around the lips. A breakout is often seen after a fever or exposure to wind or sun. The majority of individuals with HSV will not show any symptoms at all between flare-ups. Herpes labialis is contagious for individuals who have not been previously infected by the virus and for those with weakened immune systems. Fewer breakouts and shorter duration for outbreaks are the treatment goals.
Environmental Injuries
Published in Ayşe Serap Karadağ, Lawrence Charles Parish, Jordan V. Wang, Roxburgh's Common Skin Diseases, 2022
Soo Jung Kim, Alexander V. Nguyen
Management: These can typically be managed at home by drinking more water than usual, taking frequent cool baths or showers, and applying moisturizer. In especially irritated areas, applying over-the-counter hydrocortisone cream can be helpful. Nonsteroidal anti-inflammatory medications, such as aspirin or ibuprofen, can help to relieve redness, swelling, and pain. Blisters should not be popped due to introducing potential nidus for infection.
Neonatal epidermolysis bullosa: lessons to learn about genetic counseling
Published in Journal of Dermatological Treatment, 2021
Shuk Ching Chong, Kam Lun Hon, Liz Y. P. Yuen, Paul Cheung Lung Choi, W. G. Gigi Ng, Tor W. Chiu
A 1.82 kg male was born at 37 weeks gestation by cesarean section at a regional hospital. Antenatally, there was polyhydramnios. Parents are a consanguineous Pakistani couple and this was their firstborn child. There was no apparent history of bullous disorder in the family. At birth, the baby exhibited generalized ruptured bullae. His nails were not dystrophic. New blisters developed spontaneously without any trauma. The operation was performed on day 4 of life. Intra-operatively, the diagnosis of pyloric atresia (PA) was confirmed with a 1.5 cm long completely obliterated lumen, and gastroduodenostomy performed. Feeding was commenced on day 10 of life. Microscopic examination of punch skin biopsy showed detached epidermis with a blister at dermo-epidermal junction. Collagen VII stain was positive, keeping with the clinical diagnosis of EB-PA variant (4,15–17). Genetic diagnosis was refused by the parents. The child was transferred back to the referring regional hospital for care. At the age of 4 months, he succumbed during a septic episode.
Invading Deeply into Self and Everyday Life: How Oral Health-Related Problems Affect the Lives of Child Sexual Abuse Survivors
Published in Journal of Child Sexual Abuse, 2020
Siri Søftestad, Vibeke Kranstad, Therese Varvin Fredriksen, Tiril Willumsen
Some informants reported symptoms such as pain from oral mucosa, fractured teeth, and problems with dentures. Others told about recurrent lesions and blisters in the corner of the mouth, bruxism during the night, muscular fatigue, and problems with opening the mouth, as described by Fiona for example: When life is hard, I notice that I have a severe pain in the mouth. My teeth chatter, and the palate is very painful. Sometimes I have blisters. I actually always have blisters. And when I was young, I often had ulcers [points to corner of mouth]. I am not sure if this was due to my uncle [the abuser] was … from here [pulls the corners of her mouth, showing how it was forced wide open], if this was the cause of the sores. I don’t know. I have no idea.
Advances in treatment of acute sulfur mustard poisoning – a critical review
Published in Critical Reviews in Toxicology, 2019
Leila Etemad, Mohammad Moshiri, Mahdi Balali-Mood
Penetration of SM into the skin has no warning symptoms such as itching or burning, although it quickly absorbs through the skin tissue (Sugendran et al. 1998). The skin manifestations of SM intoxication present after a 6–24 h latent period (Sugendran et al. 1998; Carroll 2005; Chilcott 2005). The regions with higher humidity and temperature such as groins, hips gap, axillary, pubic (especially scrotum), and skin between the fingers are more affected (Sugendran et al. 1998; Layegh et al. 2015). A day later, bullas and vesicles reach to maximum size and become painful (Balali-Mood and Hefazi 2005a). After one week, the necrotic periderm sloughs off. However, due to the collection of a large amount of exudate and serum and electrolytes, the blisters are susceptible to superinfection. (Sugendran et al. 1998; Kehe, Balszuweit, et al. 2009)