China
Africa
Explore chapters and articles related to this topic
Trace Mineral Deficiencies – Diagnosis and Treatment
Published in Jennifer Doley, Mary J. Marian, Adult Malnutrition, 2023
Kavitha Krishnan, Julianne Werner
Manganese deficiency is very rare and is most commonly caused by inadequate manganese in the diet. Absorption is only 1–5% of dietary intake, and can be inhibited by iron supplementation as both compete for binding sites during the absorption process.2,52
Trace Minerals
Published in Luke R. Bucci, Nutrition Applied to Injury Rehabilitation and Sports Medicine, 2020
From the available evidence, which includes the unique and well-known biological roles of manganese, animal studies with deficient intakes and implanted bone powders, epidemiological data on marginal manganese intakes, and the scarce human data on deficient intakes affecting bone and joint health, it appears that adequate manganese status is essential for proper bone and joint health. Also apparent is the matter of degree of manganese deficiency and severity of bone and joint disorders. Based on animal research, the likely effects of long-term, marginal manganese status are bone loss and increased joint degeneration. Osteoporosis, osteoarthritis, and invertebral disc disease are thus postulated to be likely sequelae of insufficient manganese status in humans. The common prevalence of these conditions argues that manganese deficiencies may play a role in the initiation, progression, and/or inability to rectify these major medical problems.
Orthomolecular Parenteral Nutrition Therapy
Published in Aruna Bakhru, Nutrition and Integrative Medicine, 2018
Arturo O'Byrne-Navia, Arturo O'Byrne-De Valdenebro
Many similarities exist among species in manganese deficiency; including skeletal abnormalities, postural defects, impaired growth, impaired reproductive function, and disturbances in lipid and carbohydrate metabolism. Manganese deficiency has been associated with symptoms like fatigue, growth pains in children, irregular menses, nervous system functions alterations, and joint issues (Underwood 1977).
Salvia hispanica L. seeds extract alleviate encephalopathy in streptozotocin-induced diabetes in rats: role of oxidative stress, neurotransmitters, DNA and histological indices
Published in Biomarkers, 2022
Amal M. El-Feky, Marwa M. Elbatanony, Asmaa F. Aboul Naser, Eman A. Younis, Manal A. Hamed
The presence of vitamins E, B1, 2, 12, and C in chia seeds was consistent with Jin et al. (2012) and Kulczyński et al. (2019) findings. Plant sterols, as well as the isolated 5-coprostanol compound, have been used as antioxidants (Hallikainen et al. 2000). These findings added to the evidence that antioxidants may have a role in reducing the oxidative stress associated with diabetes. S. hispanica L. seeds oil is also reached with trace elements as copper (Cu), zinc (Zn) and magnesium (Mg) that play an important role in glucose homeostasis and as regulators in the oxidative stress condition. Changes in these components' proportions produce changes in the blood glucose levels, which can lead to diabetes (Eva et al. 2016). Copper is a crucial component of the antioxidant enzyme superoxide dismutase (Cu, Zn-SOD) (Jwaid et al2020), while Zinc is essential for the synthesis, storage and secretion of insulin (Yahya et al. 2011). Insufficient dietary Zn consumption raises the risk of coronary heart disease, hypertension, retinopathy, and thrombosis in type 2 diabetic patients (Puri et al. 2013; El-Arab et al. 2014). Manganese also helps to eliminate free radicals by acting as a cofactor with antioxidant enzymes like superoxide dismutase (Hori et al. 2000). In diabetic individuals, manganese deficiency causes oxidative stress, which leads to the development of diabetes complications (Farid 2012; Akhuemokhan et al. 2013).
Effects of static magnetic fields on bone microstructure and mechanical properties in mice
Published in Electromagnetic Biology and Medicine, 2018
Jian Zhang, Xiaofeng Meng, Chong Ding, Peng Shang
Major elements and trace elements play a critical role in human health. Excess or deficiency elements, resulting from exposure to the special environment, might induce a number of physiological effects (Brown et al., 2004). Abundant evidence had demonstrated that long-term SMF exposure could alter the concentrations of trace elements in plasma, osteoblast and bone (Jia et al., 2014; Yan et al., 1998; Zhang et al., 2014b). Our results indicated HyMF and MMF reduced the iron and manganese content in the tibia. Iron deficiency or overload can cause heavy loss of bone (Li et al., 2012). Manganese deficiency leads to disorders of bone regulatory hormones and biochemical markers of bone metabolism in serum (Wang et al., 2013). However, the reduction of iron and manganese induced by SMF did not affect the change of bone microstructure. Possibly because iron and manganese in bone tissue did not reach the level, which could influence bone metabolism. Additionally, our research suggested that MMF could increase the concentration of zinc, which was beneficial to bone formation. Several researches indicated that a strong SMF had health hazard on experimental rodent models by affecting ion transport in putative mechanism (Miyakoshi, 2006).