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Seborrhea/Seborrheic Dermatitis/Dandruff
Published in Charles Theisler, Adjuvant Medical Care, 2023
Seborrheic dermatitis (SD), or dandruff, is a chronic noncontagious inflammatory skin disorder that affects millions of Americans of all ages. The condition causes a red, flaking skin rash that can have a swollen and greasy appearance especially in the folds of the skin. It chiefly affects areas of body where sebaceous glands are most prominent such as the scalp, face, sides of the nose, eyebrows, behind the ears, or on the eyelids. The ear canals and chest or armpits can also be involved. On top of that rash, white to yellowish crusty scales accumulate on the surface and flake off.1 Most individuals with seborrhea complain of itchy skin and dandruff where white flakes of dead skin fall off the scalp and onto the shoulders. It is a lifelong condition that comes and goes. Severe medical illnesses such as AIDS, Parkinson's disease, head injury, and stroke are associated with seborrheic dermatitis.1 When a baby gets seborrhea, it is called “cradle cap.”
Nanoparticle-Stabilized Liposomes as an Effective Bio-Active Drug Molecule Delivery for Acne Treatment
Published in Namrita Lall, Medicinal Plants for Cosmetics, Health and Diseases, 2022
Catherine Wilkinson, Marco N. De Canha, Namrita Lall
Since this skin disorder is observed predominantly in pubescent teenagers, androgenic hormones such as testosterone and dihydrotestosterone are said to play a major role in acne progression (Garg, 2016). Abnormalities in androgen levels, particularly during puberty and other hormonal changes, can cause inflammation and are therefore implicated in the onset of acne (Garg, 2016; Holland et al., 1998; Iftikhar and Choudhry, 2019; Simonart, 2012). A condition known as seborrhea (excessive sebum production) is commonly observed in acne-afflicted individuals due to abnormal androgen levels. The abundance of androgen receptors present on the surface of sebaceous glands leads to the influence of androgenic hormones on the activity of these glands (Doshi et al., 1997; Jappe, 2003). Increased sebum production accompanied by abnormal keratinization of the follicles, which are both influenced by androgens, can lead to obstructed follicles and the eventual formation of non-inflammatory and inflammatory acne lesions depending on whether the bacterial infiltration and load is sufficient to cause an immune response (Garg, 2016).
Attributes of Peripheral Dopamine and Dopamine Receptors
Published in Nira Ben-Jonathan, Dopamine, 2020
An indirect evidence for the importance of the DA-DAR axis in the control of skin functions comes from non-motor dysfunctions in patients with Parkinson’s disease. Skin-related symptoms include sialorrhea (excessive salivation), seborrhea (red, itchy skin rash), hyperhidrosis (excessive sweating), sensory dysfunction/denervation of the skin, and sympathetic changes. Yet, it is unclear whether some or all the above changes are due to central and/or local deficiency of the dopaminergic system.
Effect of oral administration of Triphala, a polyphenol-rich prebiotic, on scalp sebum in patients with scalp seborrhea a randomized clinical trial
Published in Journal of Dermatological Treatment, 2022
Elham Zareie, Parvin Mansouri, Hamed Hosseini, Omid Sadeghpour, Laila Shirbeigi, Someyeh Hejazi, Majid Emtiazy
Oily skin (seborrhea) characterizes by a shiny and greasy appearance. Sebum, as a hydrophobic coating, lubricates skin and hair and provides an antibacterial shield. Seborrhea occurs because of excessive amounts of sebum produced by oversized sebaceous glands. In addition to its adverse effects on one’s mood and social interactions, seborrhea may predispose sufferers to other skin disorders, such as acne and seborrheic dermatitis (1–3). Suggestions on how to control seborrhea define in a wide spectrum. Frequent washing is recommended in cases without complications. Antifungals, contraceptives, or even isotretinoin may recommend, especially when symptoms of seborrheic dermatitis or acne are associated. Although these treatments can help reduce symptoms, their potentially more severe adverse effects, especially with long-term use, cannot be ignored (4–6). Even the need for frequent washing not only affects the sufferer’s daily life, but also may lead to sensitive or irritable skin; thus, it does not seem an efficient recommendation (1,7).
Treatment of facial telangiectasia with narrow-band intense pulsed light in Chinese patients
Published in Journal of Cosmetic and Laser Therapy, 2018
Huihui Gan, Baishuang Yue, Yan Wang, Zhong Lu
Facial pruritus was observed in six patients after treatment. Among these patients, two had chronic urticaria, four had corticosteroid-addicted dermatitis. Pruritus was relieved after treatment with antihistamine medication and cold spray in three patients with corticosteroid-addicted dermatitis, and relieved spontaneously in the other three patients. All the patients completed the study. Four patients reported decrease of seborrhea without dryness. Three patients indicated dryness of the skin after treatment, which improved by moisturizing. Clinical photographs (VISIA) before (a&c) and after (b&d) treatment showed improvement in facial telangiectasia from DPL (Figure 5).
Is maintenance treatment in adult acne important? Benefits from maintenance therapy with adapalene, and low doses of alpha and beta hydroxy acids
Published in Journal of Dermatological Treatment, 2019
Ewa Chlebus, Monika Serafin, Marcin Chlebus
It needs to be emphasized that a decrease in the severity of seborrhea was achieved in over 57% of the patients undergoing the treatment involving dermocosmetics with low doses of alpha and beta hydroxy acids, and the severity of seborrhea increased in only 4.25% of the study subjects. In the control group, the proportions are almost reversed. A reduction in the severity of seborrhea was achieved in only about 9% of the patients, and over 35% of the patients experienced an increase in the severity of seborrhea (distributions of severity of seborrhea are significantly different p < .001).