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Neuroanatomy
Published in Ibrahim Natalwala, Ammar Natalwala, E Glucksman, MCQs in Neurology and Neurosurgery for Medical Students, 2022
Ibrahim Natalwala, Ammar Natalwala, E Glucksman
Choose the most appropriate answer from the list for each statement: First-order neurones carrying vibration and proprioception sensations from the lower limb ascend in this area.The soma of a neurone originating from a Meissner’s corpuscle lies here.This enables neurones from the thoracic region to enter the cranium and supply the dilator pupillae of the eye, causing mydriasis.This artery supplies neurones in the spinal cord of the ventral corticospinal tract.This artery supplies neurones carrying sensations of discriminative (fine) touch in the spinal cord.
An introduction to skin and skin disease
Published in Rashmi Sarkar, Anupam Das, Sumit Sethi, Concise Dermatology, 2021
Recently, very fine nerve fibres have been identified in the epidermis, but most of the fibres run alongside the blood vessels in the dermal papillae and deeper in the dermis. There are several types of specialized sensory receptor in the upper dermis that detect particular sensations. Free nerve endings perceive touch, temperature, pain, and itch. Pacinian corpuscles respond to deep pressure and vibrations. Other sensory receptors include Golgi-Mazzoni corpuscles, Krause end bulbs, Meissner’s corpuscle (responding to dynamic pressure), Ruffini corpuscles (responding to stretching of the skin), and mucocutaneous end organs.
Comparative Anatomy, Physiology, and Biochemistry of Mammalian Skin
Published in David W. Hobson, Dermal and Ocular Toxicology, 2020
Meissner’s corpuscles are located in the papillary layer of the dermis of glabrous skin. These corpuscles were first described in 1852 and are also known as Wagner-Meissner corpuscles, Dogiel’s end-bulb, or as Ruffini’s end-bulbs in older literature.117 Each corpuscle is oval and approximately 100 μm long and 50 μm in diameter. Large myelinated nerve fibers (two to nine) enter the corpuscle at its base and along the sides, lose their myelin sheath, and then branch. The axoplasm is loaded with mitochondria and vesicles. These nonmyelinated axons spiral and form a bulbous ending among the flattened Schwann cells and collagen fibers. Surrounding this arrangement of expanded nerve endings and flattened cells is a connective tissue capsule which is continuous with the endoneurial sheaths of the afferent nerve fibers. The capsule is bound by elastic fibrils to the basal projections of the epidermis. The Meissner’s corpuscle is a mechanoreceptor which responds to touch116,117,137,219,249
Vibrotactile perception in Dupuytren disease
Published in Journal of Plastic Surgery and Hand Surgery, 2021
Tiffany L. Held, Mahdi Ahmadi, Rajesh Rajamani, Victor H. Barocas, Amy T. Moeller
The measured VPTs were different between men and women with women in the same age range showing greater sensitivity to vibration (Figures 7 and 8). A sensitivity difference with gender was reported by Peters et al. [31] and explained by women having smaller fingers and, therefore, a higher density of a related mechanoreceptor, the Meissner corpuscle, although Peters et al. tested passive spatial tactile acuity and not vibration sensing. As shown in Figures 7 and 8, the male subjects with DD exhibited slightly lower vibrosensitivity than the healthy controls under all conditions except 500 Hz at the palm, yet this effect fell within acceptable error.