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Ultrasound-Responsive Nanomedicine
Published in Lin Zhu, Stimuli-Responsive Nanomedicine, 2021
Tyrone M. Portera, Jonathan A. Kopechek
In addition to the widespread use of ultrasound for diagnostic imaging applications, therapeutic ultrasound applications have also been developed. Clinical therapeutic ultrasound applications primarily utilize high-intensity focused ultrasound (HIFU) to generate large pressure changes locally in tissue (Fig. 8.1). Extracorporeal shock wave lithotripsy has been used in patients since the 1980s to mechanically break up kidney and gall stones with minimal heating [1]. This non-invasive treatment is approved for clinical use in many countries, including the United States. More recently, therapeutic ultrasound has been developed for thermal ablation applications.
Ultrasonic Nondestructive Evaluation of Additively Manufactured Photopolymers
Published in Research in Nondestructive Evaluation, 2022
Luz D. Sotelo, Amelia O. Vignola, Celeste A. Brown, Kaushik Sampath, Matthew D. Guild
Ultrasonic nondestructive evaluation (NDE) methods can be used to characterize these material systems while maintaining their integrity in support of advanced polymer AM applications. Previous studies have applied ultrasonic methods to the understanding and evaluation of AM polymers made with Fused Deposition Modeling [4,7,13,14], Material Jetting (i.e. PolyJet) [5,6,8,15–18], and stereolithography [15]. However, the information available for different materials and frequency ranges is limited. In particular, shear acoustic properties [5,16] and complex elastic properties have seldom been studied in the context of AM polymers. Although often omitted, measurements of shear properties are critical for diagnostic and therapeutic ultrasound [5], design of acoustic metamaterials and structures [9–11], and advanced NDE strategies [16,19]. For instance, the accuracy of design and numerical modeling techniques (such as finite element modeling) of AM structures vastly improves with knowledge of the material shear properties [11] as opposed to when only assumed values are used [10]. Such high fidelity between finite element modeling and the measured acoustical response enables better design and analysis of 3D printed structures.
Numerical study on how heterogeneity affects ultrasound high harmonics generation
Published in Nondestructive Testing and Evaluation, 2020
Negar Kamali, Ashkan Mahdavi, Sheng-Wei Chi
Understanding ultrasound signal propagation in a heterogeneous medium is essential in many applications, especially when the size of the heterogeneity is comparable to the wavelength, such as damage detection in porous media, composites, granular material, or in diagnostic and therapeutic ultrasound [15]. The heterogeneous components distort the wave, resulting in changing the phase and generating higher harmonics. Recently, there have been more studies showing the relationship between heterogeneity and higher harmonics. Microstructural heterogeneities such as dislocation densities, precipitates, inclusions and voids and their relationship with higher harmonics have been studied previously [16–18].
Prevention and repair of orthodontically induced root resorption using ultrasound: a scoping review
Published in Expert Review of Medical Devices, 2023
Mahmoud Sedky Adly, Afnan Sedky Adly, Richard Younes, Marwan El Helou, Ivan Panayotov, Frederic Cuisinier, Delphine Carayon, Elias Estephan
Generally, in consistence with these previous studies, we suggested that the stimulatory effect of ultrasound is dose-dependent, since therapeutic ultrasound energy can be utilized in bone proteins (osteopontin, osteonectin, and bone sialoprotein) [30].