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Anti-Arthritic Potential of Gold Nanoparticle
Published in Klaus D. Sattler, st Century Nanoscience – A Handbook, 2020
Jayeeta Sengupta, Sourav Ghosh, Antony Gomes
Arthritis is one of the oldest diseases of the civilization, with first-known fossil dated back around 4500 B.C. in the Native Americans of Tennessee, USA. It has been mentioned in the ancient Greek and Hindu mythology, and the first written reference on arthritis was found in the Charaka Samhita (an Indian holistic book). There are three main categories of arthritic conditions: rheumatoid arthritis, osteoarthritis, and gouty arthritis, which can further be classified into around 100 types of arthritic conditions by the modern medicinal system. Rheumatoid arthritis mainly affects the limb joints, whereas osteoarthritis generally affects the hips, fingers, and knees. Pain is the main symptom of almost every type of arthritis, and the other symptoms include the morning stiffness, difficulty in moving joints, muscle weakness, weight loss, and fatigue.
The Modulation of IL-6 Levels by Natural Products in Arthritis-Like Animal Models
Published in Parimelazhagan Thangaraj, Lucindo José Quintans Júnior, Nagamony Ponpandian, Nanophytomedicine, 2023
Fabiolla R.S. Passos, Marilia M. Rezende, Sathiyabama R. Gandhi, Bruno A.F. Silva, Andreza G.B. Ramos, Irwin R.A. Menezes, Parimelazhagan Thangaraj, Lucindo José Quintans Júnior, Jullyana S.S. Quintans
Currently, patients diagnosed with arthritis are treated with lifestyle change, surgery and medicines that include steroidal and nonsteroidal anti-inflammatory drugs (NSAIDs), analgesics, opioids and modifiers of cartilage degradation and bone remodelling, some of which are limited by side effects (Khanna et al., 2007). NSAIDs are effective in reducing pain related to arthritis, but their use is related to the development of gastric and cardiovascular problems (Losina et al., 2013).
Articular Cartilage Pathology and Therapies
Published in Kyriacos A. Athanasiou, Eric M. Darling, Grayson D. DuRaine, Jerry C. Hu, A. Hari Reddi, Articular Cartilage, 2017
Kyriacos A. Athanasiou, Eric M. Darling, Grayson D. DuRaine, Jerry C. Hu, A. Hari Reddi
Onset of rheumatoid arthritis is most common in the fourth decade of life, though individuals of any age can be afflicted. Juvenile rheumatoid arthritis, afflicting individuals before 18 years of age, affects 294,000 children (Sacks et al. 2007) in the United States alone. Symptoms mirror those of other types of arthritis, including pain, swelling, loss of joint function, and joint contracture.
Therapeutic gloves for arthritis: development of a design framework
Published in International Journal of Fashion Design, Technology and Education, 2019
Siti Hana Nasir, Olga Troynikov
Arthritis is a chronic musculoskeletal condition causing disability, mobility limitation and pain, affecting 52.5 million adults worldwide (Centers for disease control and prevention, 2015; Klocke, 2000). It is a form of joint disorder that involves inflammation of one or more joints (Klocke, 2000; Moriyama & Bagchi, 2011; Syngle, 2006), and most frequently involves joints of the hands (Wilder, Barrett, & Farina, 2006). The symptoms of arthritis of the hand are swelling, stiffness and pain in the affected joints. There are more than 100 types of arthritis; the most common are osteoarthritis (OA) and rheumatoid arthritis (RA) (Access Economics, 2007; Syngle, 2006). Arthritis causes physical impairment and activity limitation – defined as needing help in performing daily activities – markedly reducing the quality of individuals’ lives and their productivity (Wong, Davis, Badley, Grewal, & Mohammed, 2010). The disease’s high prevalence makes it a significant contributor to the overall burden of disease (Australian Institute of Health and Welfare, 2017).
Arthritis patients’ experience and perception of therapeutic gloves
Published in International Journal of Fashion Design, Technology and Education, 2018
S. H. Nasir, O. Troynikov, N. Massy-Westropp
Arthritis is a chronic musculoskeletal condition, affecting joints where two or more bones meet (Klocke, 2000; Moriyama & Bagchi, 2011). It is a leading cause of disability, mobility limitation and pain, affecting 52.5 million adults worldwide (Centers for Disease Control and Prevention, 2015). There are more than 100 types of arthritis; the most common are osteoarthritis and rheumatoid arthritis (Access Economics, 2007; Boscheinen-Morrin & Conolly, 2001). Estimates published in 2012 reported 1.9 million Australian were diagnosed with osteoarthritis and 0.5 million with rheumatoid arthritis (Arthritis and Osteoporosis Victoria, 2013). Over 50% of Australians with arthritis are between the ages of 25 and 64 years; in their prime working age. The prevalence of arthritis increases with age, from less than 1% of people below 25 years of age to 52.1% of people aged 75 years and over. Women are more likely to have arthritis than men, particularly over 75 years (Australian Bureau of Statistics, 2012; Jenkins, 2011). Hand rheumatoid arthritis and osteoarthritis cause joint pain, stiffness, swelling and reduce hand function, especially grip strength and range of motion; these symptoms impact on everyday life and workforce participation. The prevalence of arthritis will continue to rise as the ‘baby boomers’ age, reducing the quality of individuals’ lives and contributing significantly to the overall burden of ill health (Helmick et al., 2008; Wong, Davis, Badley, Grewal, & Mohammed, 2010).
Advancements of next generation sequencing in the field of Rheumatoid Arthritis
Published in Egyptian Journal of Basic and Applied Sciences, 2023
Ankita Pati, Dattatreya Kar, Jyoti Ranjan Parida, Ananya Kuanar
Rheumatoid arthritis (RA) is perceived to be a chronic disorder that has no cure till date. However, irrespective of the progressive nature of the disorder, the harm can be slowed down or prevented from getting worse by using disease-modifying drugs. Moreover, to attain the mentioned purpose, it is important to diagnose the diseases in early stages, as the amount of harm having occurred to the patient cannot be reversed. The medical experts have advocated four major stages for Rheumatoid arthritis (Figure 1).