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Activities Supporting Work Ability in Workers with Chronic Diseases
Published in Joanna Bugajska, Teresa Makowiec-Dąbrowska, Tomasz Kostka, Individual and Occupational Determinants, 2020
As a rule, the first signs and symptoms of osteoarthritis occur in people between 40 and 60 years of age. They may affect one, several or (less often) multiple joints, and include joint tenderness, especially during movements and later also at rest and at night. The basic symptoms of osteoarthritis include pain and joint stiffness. The later symptoms include bone deformities (bone spurs formed around the affected joint) and mobility limitation. The estimated prevalence of osteoarthritis is 9.6% and 18% in the male and female population over 60 years of age, respectively. In 80% of the population, it is manifested by a limited mobility and in 25% of the limitation of usual daily life activity performance is observed (WHO 2020).
Movement
Published in Anne McLaughlin, Richard Pak, Designing Displays for Older Adults, 2020
Arthritis is a label that covers a multitude of disorders. Typical symptoms include pain and swelling, or stiffness of the joints. Osteoarthritis is one of the most common types of arthritis to affect older adults, as it is caused by “wear and tear” on the joints over a lifetime of use. The main symptoms of osteoarthritis are loss of movement, joint stiffness, swelling, and a change in the shape of the bones at the joint. This can greatly affect use of interfaces, from the fit of an input device into the hand, to accuracy of movement when interacting with a display. In general, users with arthritis will have difficulty in tasks that require gripping, fluid motion of the fingers, or using specific pressure. Small knobs, analog controls, and close-set buttons are poor choices for users with arthritis.
The therapeutic role of the components of Aloe vera in activating the factors that induce osteoarthritic joint remodeling
Published in Badal Jageshwar Prasad Dewangan, Maheshkumar Narsingrao Yenkie, Novel Applications in Polymers and Waste Management, 2018
Abhipriya Chatterjee, Patit Paban Kundu
Osteoarthritis is a chronic degenerative disease that causes the breakdown of cartilage in the joints. Symptoms include pain, stiffness, and swelling. Osteoarthritis causes progressive breakdown and wearing away of the cartilage, leaving the bone ends unprotected. As this occurs, the joint can become painful, stiff, and difficult to move and eventually swollen.30
Effect of knee braces and insoles on clinical outcomes of individuals with medial knee osteoarthritis: A systematic review and meta-analysis
Published in Assistive Technology, 2022
Mobina Khosravi, Taher Babaee, Aliyeh Daryabor, Maryam Jalali
Knee osteoarthritis is a common degenerative joint disease that is increasing due to aging in populations (Felson et al., 1995). Loading on the medial compartment of the knee joint is 2.5 times greater than the lateral compartment that can increase the incidence of medial compartment osteoarthritis. Decreased quality of life (Lewinson et al., 2016), physical function impairment (Hjartarson & Toksvig-Larsen, 2018) and pain (Thoumie et al., 2018) are some of the its complications. The non-surgical treatments are often the first choice with the aims of preventing its progression and improving function and pain (Zhang et al., 2008). Different non-surgical treatments have been recommended by the Osteoarthritis Research Society International (OARSI), including medications, self-care education, exercises, physical therapy, weight loss, lifestyle modification, and conservative interventions such as knee braces and lateral wedged insoles (Bannuru et al., 2019).
Improved skin-permeated diclofenac-loaded lyotropic liquid crystal nanoparticles: QbD-driven industrial feasible process and assessment of skin deposition
Published in Liquid Crystals, 2021
Tejashree Waghule, Shalini Patil, Vamshi Krishna Rapalli, Vishal Girdhar, Srividya Gorantla, Sunil Kumar Dubey, Ranendra Narayan Saha, Gautam Singhvi
Diclofenac diethylamine (DDE) is one of the most potent NSAIDs (Non-steroidal anti-inflammatory drugs) used as first-line therapy to reduce pain/inflammation. It is indicated for musculoskeletal diseases like osteoarthritis and rheumatoid arthritis. Osteoarthritis involves severe joint pain and inflammation due to cartilage degeneration and affects millions of people worldwide. Diclofenac shows its action through inhibition of the cyclooxygenase pathway (COX-2 enzyme inhibition) and modulation of arachidonic acid utilisation which is involved in inflammation and pain signalling [1]. It is currently available in the market in different dosage forms like dispersible tablet, sustained-release tablet, enteric-coated tablet, capsule, suppository, injection, and eye drops. All these formulations have different advantages but diclofenac is inherently associated with certain limitations like shorter half-life (2–3 h), high first-pass metabolism, poor bioavailability (40–60%), high dosing frequency, adverse effects related to the gastrointestinal system and cardiovascular system. Thus, to overcome all these limitations associated with the effective delivery of diclofenac, a non-oral delivery system turns out to be the best option for long-term therapy [2].
A framework for studying risk factors for lower extremity musculoskeletal discomfort in nurses
Published in Ergonomics, 2020
Jing Li, Carolyn M. Sommerich, Esther Chipps, Steven A. Lavender, Elizabeth A. Stasny
Nurses who were obese or morbidly obese were more likely to have foot/ankle MSK symptoms that limited their activity, when compared with nurses who were underweight or had normal BMI (odds ratio 4.43; Reed et al. 2014). Obesity has also been identified as a primary risk factor for knee osteoarthritis (Kulkarni et al. 2016). Other individual factors could potentially affect the nurse’s lower extremity health, including age, gender, previous injury, health status (overall and foot/leg health), footwear choice (including inserts and compression stocking; Chiu and Wang 2007; Kurup, Clark, and Dega 2012), and personal habits/behaviours and responsibilities (smoking, sleeping pattern, other physical activities other side work, such as housework, exercise/workout, physical care for children or others; Samaha et al. 2007).