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Data mining to Hepatitis B based on WEKA
Published in Amir Hussain, Mirjana Ivanovic, Electronics, Communications and Networks IV, 2015
This data set includes 11 different properties. They are age, A/G ratio (the ratio between albumin and globulin), total Bilirubin (Total bilirubin is the sum of direct bilirubin and indirect bilirubin. Total bilirubin is commonly known as jaundice, mainly used to diagnose liver disease or whether there is abnormal bilirubin), direct Bilirubin (Measuring direct bilirubin is mainly used to identify the type of jaundice), total proteins (Total protein is composed of albumin and globulin), albumin (Synthesized by the liver, is a normal human serum total protein in the major protein component. Maintaining blood albumin colloid osmotic pressure, metabolic material transport), gender, SGPT (Alanine aminotransferase, is mainly in the liver, heart and skeletal muscle. Liver cells or some tissue damage or necrosis, can make blood alanine aminotransferase increased. Many diseases can cause abnormal transaminases clinically that must be identified), SGOT (Aspartate aminotransferase, also known as aspartate aminotransferase, ALT is the more important one. It is an indicator of clinical medicine liver function tests, used to determine whether the liver is damaged), Alkphos (Alkaline phosphatase is widely distributed in human organs in various organs, including liver, followed by a maximum of kidney, bone, intestine, placenta and other tissues. When the liver is damaged or disordered, alkaline phosphatase will flow into the blood via lymphatic and sinusoidal. And because of the disorder of intrahepatic biliary excretion, bile reflux, can cause a conspicuous increase of serum alkaline phosphatase.
Susceptibility of young and adult rat kidneys to impacts of mosquito coil fumes
Published in Egyptian Journal of Basic and Applied Sciences, 2021
On the other hand, even the experiment lasted only for 4 weeks, a significant decrease in serum total protein and an increase in urine protein and microalbuminuria were observed in young and adult exposed groups. These data support the finding that longer exposure may lead to a significant decrease in body weight, as observed by Pauluhn and Mohr [19] who exposed animals for 13 weeks to coil fumes. In parallel, serum and urine creatinine, as well as urea levels showed significant elevation, especially in young exposed groups compared to adults. Taiwo Idowu et al. [9] attributed this to the affected protein biosynthesis in the liver and increased catabolism through repeated exposure to coil fumes containing components that may interfere with metabolic functions leading to metabolic derangement in liver cells [20]. The authors provided another explanation that serum total protein may be decreased due to tissue utilization of blood protein to compensate for metabolic alterations in different organs. Besides, another biomarker of protein catabolism is the significant increase in serum uric acid levels, which also could contribute to the impairment of kidney functions, as observed by Goma and Tohamy [21] in animals under oxidative stress induced by heavy metals exposure.