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Next Era of Computing with Machine Learning in Different Disciplines
Published in Abid Hussain, Garima Tyagi, Sheng-Lung Peng, IoT and AI Technologies for Sustainable Living, 2023
R. Sabitha, J. Shanthini, S. Karthik
Anaemia disease categorized into different types based on the CBC test values. In this model, anaemia types nomenclature illustrated (see Table 4.1) and classified according to MCV value into the three essential kinds of microcytic (MCV < 80) ft, normocytic (MCV = 80–100) ft and macrocytic (MCV > 100) ft anaemia and classified using MCHC (Mean corpuscular haemoglobin concentration) into normochromic (MCHC = 32–36) g/dL and hypochromic (MCHC < 32) g/dL anaemia. RDW (Red Cell Distribution Width) used to measure the anaemia and it is high if (RDW > 14.6) and normal if (RDW = 11.6–14.6) (Green, 2012; Sanap et al., 2011).
Serum ferritin and vitamin D evaluation in response to high altitude comparing Italians trekkers vs Nepalese porters
Published in European Journal of Sport Science, 2021
Laura Magliulo, Danilo Bondi, Tiziana Pietrangelo, Stefania Fulle, Raffaela Piccinelli, Tereza Jandova, Gaetano Di Blasio, Mattia Taraborrelli, Vittore Verratti
High-altitude physiology has been extensively studied (West, 2016; Young & Reeves, 2002) and it is continuing to move forward, both from clinical, health and sports perspective. The hypobaric environmental condition posed by high altitude elicits through hypoxia a decrease in the partial pressure of oxygen (PpO2) in the blood and consequently in tissues, resulting in a modification of hematological parameters (Mairbäurl, 2019; Young & Reeves, 2002). Considering the importance of erythropoiesis in hypoxic acclimatization or adaptation processes, iron homeostasis plays a crucial role (Yanamandra et al., 2019) and should be studied in hypoxic demands. Blood biomarkers from Complete Blood Count (CBC) analysis such as hemoglobin concentration (HGB), serum ferritin (sFER), red blood cell count (RBC), red cell distribution width (RDW), mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) are considered as the most sensitive and accurate parameters to evaluate iron homeostasis (Tailor, Patel, Prasad Pandya, & Mangukiya, 2017), also in response to altitude (Al-Sweedan & Alhaj, 2012; Badrick, Richardson, Arnott, & Lidbury, 2017).
Toxicity and human health assessment of an alcohol-to-jet (ATJ) synthetic kerosene
Published in Journal of Toxicology and Environmental Health, Part A, 2020
David R. Mattie, Brian A. Wong, Karen L. Mumy, Shawn M. McInturf, Michael D. Grimm, Nathan, M. Gargas, Linda M. Shafer, Richard C. Striebich, Teresa R. Sterner
Terminal blood samples collected via the caudal vena cava were analyzed for clinical chemistry and hematology endpoints. Prothrombin time in plasma (PT-P) and international normalized ratio (INR) were determined with a blood clot analyzer (GEM PCL Plus, Instrumentation Laboratory, Lexington, MA). Samples of whole blood with anticoagulant were examined with a blood analyzer (Hemavet 950, Drew Scientific, Dallas, TX) to measure counts of white blood cells (WBC), neutrophils, lymphocytes (cells/µl), monocytes (cells/µl), eosinophils (cells/µl), and basophils (cells/µl); neutrophils (%), lymphocytes (%), monocytes (%), eosinophils (%), basophils (%); counts of red blood cells (cells/µl) and platelets; and hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin in cells, mean corpuscular hemoglobin concentration in blood, red cell distribution width, mean platelet volume. Samples of serum were assessed using a chemistry analyzer (Vet Test 8008 and Vet Lyte, IDEXX Laboratories, Westbrook, ME) to determine albumin, alkaline phosphatase, alanine transaminase, aspartate transaminase, blood urea nitrogen, cholesterol, creatine kinase, creatinine, globulins, glucose, total bilirubin, total protein, triglycerides, sodium, potassium, chloride.
Does occupational ionizing radiation exposure in healthcare workers affect their hematological parameters?
Published in Archives of Environmental & Occupational Health, 2023
Nejdiye Güngördü, Seher Kurtul, Ayşenur Özdil, Mehmet Sarper Erdoğan
This study evaluated the 2020-2021 periodical health examination data for the healthcare personnel working in the Hospital of Cerrahpaşa School of Medicine; the data was obtained from the Occupational Health and Safety Unit. Hematological parameters obtained during the periodic examinations of a total of 339 healthcare workers with and without IR exposure were compared (169 radiation workers and 170 controls). The IR exposure group was matched with the control group in terms of age and gender. In blood samples of healthcare workers, white blood cell (WBC) count, lymphocytes (Lymph), neutrophils (Neu), monocytes (Mono), eosinophil, basophil, red blood cell (RBC) count, hemoglobin (Hb), hematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean erythrocyte hemoglobin concentration (MCHC), and red-cell distribution width (RDW), platelet (Plt) were measured. Those exposed to occupational IR for at least 1 year were included in the IR group. Participants with severe anemia, known history of diabetes, cardiopulmonary disease, acute or chronic infection, autoimmune disease, history of malignancy, and pregnant women were excluded from this study. Hematological parameters were assessed using the Sysmex–Mmindray–Njhoneoden analyzer in a standard laboratory. Written informed consent was obtained from each individual participating in the study. Annual ambient and personal IR measurements were performed regularly in the hospital, and the results were within the limit values determined by the ICRP. The radiation committee of the hospital monitors the annual individual dosimetry measurements of the healthcare workers and informs the occupational health and safety unit when abnormal measurements are detected.