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Discrete Random Variables
Published in William M. Mendenhall, Terry L. Sincich, Statistics for Engineering and the Sciences, 2016
William M. Mendenhall, Terry L. Sincich
Premature aging gene. Ataxia-telangiectasia (A-T) is a neurological disorder that weakens immune systems and causes premature aging. Science News reports that when both members of a couple carry the A-T gene, their children have a 1 in 5 chance of developing the disease. Consider 15 couples in which both members of each couple carry the A-T gene. What is the probability that more than 8 of 15 couples have children that develop the neurological disorder?Consider 10,000 couples in which both members of each couple carry the A-T gene. Is it likely that fewer than 3,000 will have children that develop the disease?
Radiation Hazards
Published in Dag K. Brune, Christer Edling, Occupational Hazards in the Health Professions, 2020
After prolonged exposure to sunlight over a period of years, the dermis will begin to degenerate, with a decrease in elasticity due to degeneration of the collagen fibers combined with other histological changes. The visible symptoms will be deep furrows in the skin, giving an appearance of premature aging.
Construction Management
Published in Abdul Razzak Rumane, Handbook of Construction Management, 2016
Repeated exposure to the sun can cause premature aging effects. Sun-induced skin damage causes wrinkles, easy bruising, and brown spots on the skin. For all the ladies here, to maintain your pretty and young look and also for men their handsome appearance, avoid being exposed to sun. It is not too late!
A simple method for functionalization of polypyrrole-coated cotton fabrics by reduced graphene oxide for UV screening
Published in Inorganic and Nano-Metal Chemistry, 2023
Dhineshbabu N. R., Raghavendra Babu B., Arunmetha S., Arivanandan M., Jayavel R.
The UV-screening capabilities of the UC and coated cotton fabrics are shown in Figure 8. In the wavelength region between 280 and 400 nm, the typical UV–vis transmission percentage of coated and UC fabrics were examined (Figure 8). UVA (400-315nm), UVB (315–280 nm), and UVC (280–100 nm) are the three forms of UV radiation. UVC, UVB, and UVA are entirely absorbed, partially absorbed, and not absorbed by the ozone layer and atmosphere, respectively. UV radiation is present throughout the year and can induce premature aging and cancer in those who are overly exposed to it. Its presence is extremely intense during the summer, and too much exposure can cause tanning, sunburn, aging, cancer, and other problems. The in-vitro method is a technique that is used to study something in which UV-rays are transmitted directly and scattered, which are essential elements in determining a textile's UV protection.[53]
Air pollution and molecular changes in age-related diseases
Published in International Journal of Environmental Health Research, 2022
B. Hermanova, P. Riedlova, A. Dalecka, V. Jirik, V. Janout, R. J. Sram
Studying the association between above-mentioned molecular changes and polluted air is a relatively new direction in research. In order to enable results to be compared, it would be advisable to create standards for exposure estimation modelling, as well as for epidemiological studies in the real environment. Further research should focus on studying how the body adapts to a polluted environment. Although this issue has not been fully explored yet, it is clear that an adapted body has a different response than an unadapted organism and some of these adaptation mechanisms could be hereditary. It is known, that children born to mothers exposed to pollution show detectable changes at the molecular level at birth. Based on this assumption, prenatal exposure should always be considered in studies. It is necessary to identify congenital and acquired molecular changes separately. These mechanisms must be properly studied so that human adaptation to external stressors is differentiated from the simple presence of compensation processes. In the short-term, the body is capable of exerting a great compensatory effort, which could temporarily improve certain molecular parameters. Such chronic strain on the body then results in premature aging and a shortened life.
Anti-glycation effect and the α-amylase, lipase, and α-glycosidase inhibition properties of a polyphenolic fraction derived from citrus wastes
Published in Preparative Biochemistry & Biotechnology, 2020
Annayara C. F. Fernandes, Ádina L. Santana, Isabela M. Martins, Debora K. T. Moreira, Juliana A. Macedo, Gabriela A. Macedo
Researches on the development of natural and novel AGEs inhibitors increased in order to supply the urgent demand to retard or prevent premature aging and complications caused by several diseases. Polyphenols are plant-based secondary metabolites considered as potential glycation inhibitors because of their ability to scavenge free radicals, to capture reactive dicarbonyl compounds, and to regulate gene expression.[6]