China 
Africa 
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Application of Nanobioformulations for Controlled Release and Targeted Biodistribution of Drugs
Published in Anil K. Sharma, Raj K. Keservani, Rajesh K. Kesharwani, Nanobiomaterials, 2018
Josef Jampílek, Katarina Král’ová
Porphyrin-CD conjugates as a nanosystem for versatile drug delivery and multimodal cancer therapy were reported by Králová et al. (2010). NPs of CD-based star polymers prepared using β-CD as hydrophilic core and methyl methacrylate and tert-butyl acrylate as hydrophobic arms showed prolonged release profile of idarubicin. NPs were internalized with A549 cells related to Caco-2 cells in time-dependent manner with preferential accumulation in cytoplasm with superior uptake of positively (CS-modified NPs) over negatively charged particles (Nafee et al., 2015).
Development of conductive textile fabric using Plackett–Burman optimized green synthesized silver nanoparticles and in situ polymerized polypyrrole
Published in Green Chemistry Letters and Reviews, 2023
Ashleigh Naysmith, Naeem S. Mian, Sohel Rana
Considerable research has established that silver nanoparticles (AgNPs) possess superlative electrical conductivity, and established biocompatibility (10, 11). AgNPs have been used in biomedical devices, drug delivery, multimodal cancer therapy, wound dressings, SARS-CoV-2 inhibition, and antimicrobial clothing (10–17). Research has shown that AgNPs are not toxic to eukaryotic cells but are toxic to prokaryotic cells, hence their success as antimicrobial agents (10, 11). Despite this, there remains a lack of consensus on AgNPs’ toxicity to health and the environment (10, 13). Aboelmaati et al. conducted in vivo research to find that green synthesized AgNPs were more biocompatible than conventionally synthesized AgNPs (13). Conventional AgNP synthesis methods use toxic precursors and high energy costs (10). The results of Aboelmaati et al. demonstrated that the research animals had a higher tolerance to the green synthesized AgNPs as compared to conventionally synthesized AgNPs (13).
α-tocopherol as a selective modulator of toxicogenic damage induced by antineoplastic agents cyclophosphamide and doxorubicin
Published in Journal of Toxicology and Environmental Health, Part A, 2023
Victor Alves de Oliveira, Andressa Naiane Rodrigues Monteiro Fernandes, Lauana Maria dos Santos Leal, Paloma Alves Ferreira Lima, Ana Rafaela Silva Pereira, Irislene Costa Pereira, Helber Alves Negreiros, Joilane Alves Pereira-Freire, Felipe Cavalcanti Carneiro da Silva, Ana Amélia de Carvalho Melo Cavalcante, Francisco Leonardo Torres-Leal, Adriana de Azevedo Paiva, João Marcelo de Castro e Sousa
Significant progress has been made in the last decades in cancer treatment; however, a challenge to be overcome is the development of more selective active agents for application in multimodal cancer therapy. Drugs with greater selectivity aim to reduce harmful effects in healthy cells with high proliferation rates such as in skin or gastrointestinal tract, since these cells resemble malignant cell activities in cellular proliferation, and are the predominant target of severe side effects (Celik et al. 2021; Durães et al. 2014; Ferreira et al. 2013; Patterson et al. 2018).