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Utilization of Fisheries' By-Products for Functional Foods
Published in Se-Kwon Kim, Marine Biochemistry, 2023
Muhamad Darmawan, Nurrahmi Dewi Fajarningsih, Sihono, Hari Eko Irianto
Fish oils are readily digested to produce the energy and have been reported to exhibit several bioactivities (Kim and Mendis, 2006). The benefit of omega-3 fatty acids in fish oil is very essential for cardiovascular diseases (Durmus, 2018). Thus, consuming DHA and EPA can prevent the formation of cardiovascular disorders by reducing risk factors, such as blood pressure, platelet aggregation, triglyceride concentrations and heart arrhythmias (Fung et al., 2009; Raatz and Bibus, 2016). In addition, a diet enriched with fish oil has been reported to prevent cognitive disorders for older people yet induce brain development for children (Pinel et al., 2014; Graciano et al., 2016; He et al., 2017). It is reported that a diet with high doses of fish oil (>6 g/day) contained omega-3 fatty acids (4 g/day) in patients with hypertriglyceridemia significantly lowered the triglyceride content in blood (Asztalos et al., 2016). Furthermore, a study on fortified foods with fish oil has correlated it with health benefits, including antihyperlipidemic, anti-inflammatory, antithrombotic and antihypertensive (Gonzalez-Sarrias et al., 2013).
Novel Microbial Compounds as a Boon in Health Management
Published in Jyoti Ranjan Rout, Rout George Kerry, Abinash Dutta, Biotechnological Advances for Microbiology, Molecular Biology, and Nanotechnology, 2022
Shubha Rani Sharma, Rajani Sharma, Debasish Kar
The pancreas is the organ situated behind the stomach. Its inflammation is quite painful and the condition is known as acute pancreatitis. It can be mild, moderate, severe to critically acute. In the case of severe and critical acute pancreatitis, there is persistence organ failure (Kylänpää et al., 2012). If this persists, it can lead to death. The main challenging issue with the disease is its diagnosis. It is quite difficult to access the organ without surgery. It has been observed that the sufferer has an increased level of amylase or lipase. But this is not always the case. In such a situation, abdominal imaging which includes computed tomography, transabdominal ultrasound, endoscopic ultrasound, and magnetic resonance cholangiopancreatography is preferred. Gallstones, idiopathic, chronic alcohol consumption, drug-induced hypertriglyceridemia, and idiopathic are the major risk factors for acute pancreatitis (Pang et al., 2018). Of this, gallstone is the main cause followed by alcohol consumption. Inappropriate trypsin activation is also one of the major causes of acute pancreatitis (Whitcomb, 2006). Its treatment also needs a specification for the risk factor. Acute pancreatitis due to gallstone needs to be operated on first. In the case of necrosis, antibiotics are to be given to avoid morbidity (Büchler et al., 2000). Another effective way of treatment is the introduction of probiotics. In most cases, it was not proved much effective (Gou et al., 2014) while some have shown a positive effect of probiotics on acute pancreatitis treatment (Hooijmans et al., 2012).
Herbal Therapies
Published in Anil K. Sharma, Raj K. Keservani, Surya Prakash Gautam, Herbal Product Development, 2020
H. Shahrul, M. L. Tan, A. H. Auni, S. R. Nur, S. M. N. Nurul
Cardiovascular disease remains as major cause of death worldwide. Cardiovascular diseases (CVDs) comprise coronary heart disease, cerebrovascular disease, rheumatic heart disease, heart failure and related diseases. CVDs cause the death of an average17.9 million people every year, constituting 31% of all global deaths. Most of the CVD related deaths are related to heart attacks and strokes (WHO, 2018). Epidemiological studies reported risk factors such as environment and genetic origin were linked to atherosclerosis, namely increased blood pressure, elevated fasting blood glucose, hypertriglyceridemia, hypercholesterolemia, central obesity, smoking and sedentary lifestyle (Hajar, 2017; Smith, 2007). A major complication is the development of atherosclerotic plaque that results in myocardial infarction, a multiple consequence of foam cells formation, oxidation of low-density lipoprotein (LDL), production of free radicals, and disruption of endothelial function in artery.
Ameliorative effect of quercetin on pancreatic damage in rodent: a meta-analysis
Published in Egyptian Journal of Basic and Applied Sciences, 2023
Tri Wiyono, Khoirun Nisa, Sri Handayani, Anjar Windarsih, Septi Nur Hayati, Martha Purnami Wulanjati, Eti Nurwening Sholikhah, Woro Rukmi Pratiwi
Hyperlipidemia is defined as an increase in plasma cholesterol, triglycerides, or both [1,2]. Hypertriglyceridemia has been reported to be positively correlated with cases of CVD and pancreatitis [3]. Oxidative stress conditions on beta cells and changes in plasma viscosity by triglycerides are mentioned as triggers for pancreatic cell damage, ranging from inflammation to necrosis [4,5]. In the case of pancreatic cells, insulin secretion is impaired by the accumulation of free fatty acid (FFA), which can also lead to apoptosis [6]. Therefore, treatment of damaged pancreatic cells is needed, especially to reduce the dependence of diabetic patients on insulin therapy.