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The combined effects of noise and vibration stress on sex hormone levels, fertility capacity, and the protective role of cinnamon extract in rats: an experimental study
Published in Archives of Environmental & Occupational Health, 2022
Hamideh Pirami, Ali Khavanin, Farshad Nadri, Ali Tajpoor, Younes Mehrifar, Zohreh Mazaheri Tirani
The gonadotropin releasing hormone (GnRH) is secreted in the hypothalamus and stimulates the release of LH and FSH from the anterior pituitary gland. LH is the main stimulus for testosterone secretion and FSH mainly stimulates spermatogenesis.51 Stress can reduce GnRH release by affecting the hypothalamus and reducing LH and FSH secretion. On the other hand, stress reduces the pituitary's ability to respond to GnRH. The results of the present study confirmed that stress can inhibit GnRH release by activating inhibitory pathways connected to GnRH nerve endings in the median eminence, thereby reducing LH and FSH secretion.52