Explore chapters and articles related to this topic
European regulatory guidance
Published in Sarfaraz K. Niazi, Biosimilars and Interchangeable Biologics, 2016
Follicle stimulating hormone (FSH) is a pituitary glycoprotein hormone that plays a key role in regulating reproductive function in both males and females. FSH is a heterodimeric hormone composed of two linked subunits. The alpha subunit (92 amino acids) is common to other glycoprotein hormones, whereas the beta subunit (111 amino acids) is specific. Both subunits contain oligosaccharide structures. As a consequence of carbohydrate variability, different isoforms of hFSH with different sialic acid content exist. Isoforms with a high sialic acid content remain longer in circulation. Physicochemical and biological methods are available for characterization of the protein.
Glossary of scientific and technical terms in bioengineering and biological engineering
Published in Megh R. Goyal, Scientific and Technical Terms in Bioengineering and Biological Engineering, 2018
Follicle stimulating hormone (FSH) refers to a hormone, secreted by the anterior pituitary gland in mammals, that stimulates the ripening of the specialized structures in the ovary (Graafian follicles) that produce ova in female mammals; and in males, the formation of sperm in the testis.
The effect of the menstrual cycle on the sense of touch, grip strength and manual dexterity of dental students
Published in International Journal of Occupational Safety and Ergonomics, 2022
Emir İbrahim Işik, Koray Soygun, Öykü Ceren Kahraman, Elif Figen Koçak
FSH is expressed according to the negative feedback mechanism with the level of oestrogen in the blood. Increased oestrogen in the blood causes a fall in FSH. On day 1 of the menstrual cycle, FSH is high and oestrogen is low, and on day 14 of the cycle, oestrogen is at the highest level and FSH at the lowest level [16].