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Nutraceutical Efficiency of Fucan Polysaccharides from Marine Sources
Published in Shakeel Ahmed, Aisverya Soundararajan, Marine Polysaccharides, 2018
Ashwini Rav, S. Vijayanand, S. Aisverya, P. N. Sudha, J. Hemapriya
Anticoagulants are medicines used for the prevention of blood clots in any blood vessel of the body. Sometimes, they are also referred to as ‘blood thinners’ (American Heart Association). To treat this blood clotting several anticoagulating agents have been used, and the most common drug used for this purpose is heparin. Heparin is a pentasaccharide with specific glucose and sulphate linkages which is used to treat blood clotting [60, 61]. These molecules promote protease and antithrombin, resulting in no blood clot [62]. Though this molecule is highly used as blood thinner it poses several side effects such as development of thrombocytemia, haemorrhage, ineffective congenital and antithrombin deficiencies, inability to inhibit the fibrin-bound thrombin, etc. In addition, since these molecules are collected from pig intestine or bovine lungs, they also pose an incidence of prion-related diseases [63–65]. Therefore, an alternative to heparin with similar effectiveness has to be found to overcome these problems.
Blood in flow. Basic concepts
Published in Annie Viallat, Manouk Abkarian, Dynamics of Blood Cell Suspensions in Microflows, 2019
Etienne Loiseau, Annie Viallat, Manouk Abkarian
Platelets, around 5% of the cells in blood, are cell fragments engaged along with the coagulation factors in the formation of a blood clot. Platelets are small discs with a diameter of about 2.5 μm. They are produced when large cells called megakaryocytes break into pieces, each one making 2000 - 3000 platelets as it comes apart. Chapter 7 is dedicated to the behavior of platelets, which is also discussed in Chapter 4.
Bioprinting of living aortic valve
Published in Ali Khademhosseini, Gulden Camci-Unal, 3D Bioprinting in Regenerative Engineering, 2018
D.Y. Cheung, S. Wu, B. Duan, J.T. Butcher
Despite being a durable option for patients, there are serious complications and lifestyle limitations for patients with MHV (Misawa 2014). Patients are required to take life-long anticoagulation medication to manage and reduce risks of thromboembolism caused by blood clots formed due to shearing of the blood cells; however, this medication can also cause hemorrhage (Labaf et al. 2016). In addition, pediatric and young patients must consider additional surgeries for valve resizing (Masuda et al. 2008).
Combined impact of Brownian motion and thermophoresis on nanoparticle distribution in peristaltic nanofluid flow in an asymmetric channel
Published in International Journal of Ambient Energy, 2022
Bivas Bhaumik, Satyasaran Changdar, Soumen De
Blood clots can be formed when the blood flow rate is slow and the platelets are more likely to stick together. So the observation of streamlines is necessary to see the formation of internal confined boluses of the fluid. An interesting and unique phenomenon in peristaltic motion is trapping phenomena. It is basically the expansion of an internally circulating bolus of fluid by protected streamlines. These phenomena have been viewed by plotting stream lines in Figures 8 and 9. Figure 8(b–d) display the effects of different values of Hartmann number on streamlines. From these figures it is observed that the number of bolus remains same but there is a small increment in the diameter of the bolus. In Figure 9(a–c) it is inspected that the diameter of the bolus increases but the number of confined bolus reduces as the parameter rises. But a quite opposite nature have been seen with the increment of the angle inclination (ϕ). That means when the tube rises upwards the number of trapped bolus increases and the diameter of the bolus also increases, which are apparent from Figure 9(d–f).
Prediction of cardiovascular disease using deep learning algorithms to prevent COVID 19
Published in Journal of Experimental & Theoretical Artificial Intelligence, 2023
Malathi S, Arockia Raj Y, Abhishek Kumar, V D Ashok Kumar, Ankit Kumar, Elangovan D, V D Ambeth Kumar, Chitra B, a Abirami
Cardio vascular disease (CVD) is the major cause of death rate globally. The highest leading cause of mortality is Ischaemic heart disease (IHD). Heart and blood vessel disease is also referred as heart disease which includes more problems like atherosclerosis, which develops condition plaque that is developed in the walls of the arteries. Therefore, the narrowed arteries by this build-up, makes very hard for blood flow into it. If a blood clot is formed in the blood vessel then it will block the flow of blood and cause a heart attack or stroke. In developed countries like the United States and the United Kingdom, the main cause of deaths are due to diseases like heart disease and stroke, which are common among adult men and women.