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Hybrid Approach towards Malaria Parasites Detection from Thin Blood Smear Image
Published in Siddhartha Bhattacharyya, Anirban Mukherjee, Indrajit Pan, Paramartha Dutta, Arup Kumar Bhaumik, Hybrid Intelligent Techniques for Pattern Analysis and Understanding, 2017
Sanjay Nag, Nabanita Basu, Samir Kumar Bandyopadhyay
In mammals, oxidation of tissues is performed by binding the oxygen molecules to the hemoglobin contained within the circulating discoid shaped and non-nucleated red blood cells (RBCs) or erythrocytes. Malaria infects and lives a parasitic life within the host RBC and destroys the same eventually. For computerized algorithms identification and differentiation of infected and normal RBCs are vital. The possible hinderence in the segmentation process are the presence of white blood cells (WBCs) or leukocytes that are the primary defense system of the body against infections. In normal circulation of blood, there are approximately 7000 WBCs per microliter of blood. They constitute about 1% of the total blood volume in healthy adult individuals. Based on the presence/absence of granules (sacs containing digestive enzymes or other chemical substances) in the cytoplasm, the WBC is considered to be a granulocyte or agranulocyte. Neutrophils, basophils and eosinophils are granulocytes that differ in the lobular structure of nucleus. Lymphocytes and monocytes have single-lobed nucleus and void of granules and constitutes agranulocytes.
Computer-aided system for Leukocyte nucleus segmentation and Leukocyte classification based on nucleus characteristics
Published in International Journal of Computers and Applications, 2020
White Blood Cells (WBCs), also termed as Leukocytes provide immunity against diseases and also help in protecting the body against infections. They are produced by the hematopoietic stem cells in the bone marrow. The WBCs are distinguishable from Platelets and Erythrocytes due to the presence of Nucleus. WBCs are broadly classified into Granulocytes and Agranulocytes based on their structure. The broader categories can be further divided into five types namely, Basophil, Neutrophil, Eosinophil, Monocyte, and Lymphocyte. Characterization of WBCs is shown in Table 1.