Synovial Sarcoma
Published in Dongyou Liu, Tumors and Cancers, 2017
Dongyou Liu
Tumors of uncertain differentiation may be differentiated into (1) benign (intramuscular myxoma [including cellular variant], juxta-articular myxoma, deep [“aggressive”] angiomyxoma, pleomorphic hyalinizing angiectatic tumor, and ectopic hamartomatous thymoma), (2) intermediate (rarely metastasizing) (angiomatoid fibrous histiocytoma, ossifying fibromyxoid tumor [including atypical and malignant], and mixed tumor [myoepithelioma and parachordoma]), and (3) malignant (synovial sarcoma, epithelioid sarcoma, alveolar soft part sarcoma, clear cell sarcoma of soft tissue, extraskeletal myxoid chondrosarcoma [“chordoid” type], primitive neuroectodermal tumor [PNET]/extraskeletal Ewing tumor, desmoplastic small round cell tumor, extra-renal rhabdoid tumor, malignant mesenchymoma, neoplasms with perivascular epithelioid cell differentiation [PEComa], clear cell myomelanocytic tumor, and intimal sarcoma) [1].