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Echocardiographic Features of Hypertrophic Cardiomyopathy
Published in Srilakshmi M. Adhyapak, V. Rao Parachuri, Hypertrophic Cardiomyopathy, 2020
Speckle tracking echocardiography, a recently introduced specialized application and a validated method that is not angle-dependent, is now widely used in routine echocardiography to measure myocardial deformation or strain as a measure of LV systolic function [30]. It can provide measurements of both regional and global functions of the LV and the RV and LA chambers. This unique ability of STE provides a way to identify regional areas of myocardial dysfunction (due to fibrosis), seen as low segmental strain and paradoxical systolic stretch (Figure 4.20). Many studies have described a good correlation between reduced strain and myocardial fibrosis. The parametric strain image (bull’s eye) can differentiate to some extent the LVH of hypertensive heart disease with that of HCM, with its striking involvement of reduced strain in the septum being indicative of HCM.
Survivorship: Pediatric cancer survivors
Published in Susan F. Dent, Practical Cardio-Oncology, 2019
Shahnawaz Amdani, Neha Bansal, Emma Rachel Lipshultz, Michael Jacob Adams, Steven E. Lipshultz
The most common measures used in serial follow-up of patients with anthracycline-related cardiomyopathy are LVFS and LVEF (113). However, as mentioned previously, these measures may not detect subclinical cardiotoxicity, which may occur in up to 60% of treated patients (128). Moreover, LVFS and LVEF are load-dependent measures. Recently, strain and strain-rate imaging measured by speckle tracking echocardiography has been used. Among 56 asymptomatic patients evaluated 2–15 years after anthracycline treatment (doses <300 mg/m2), although traditional measures of ventricular function (LVFS and LVEF) did not differ, systolic myocardial deformation decreased, as did radial and longitudinal peak systolic strain (69). However, long-term evaluations of pediatric cancer survivors exposed to cancer chemotherapeutics using strain imaging have not been validated.
Predicting the Biomechanics of the Aorta Using Ultrasound
Published in Ayman El-Baz, Jasjit S. Suri, Cardiovascular Imaging and Image Analysis, 2018
Mansour AlOmran, Alexander Emmott, Richard L. Leask, Kevin Lachapelle
Two-dimensional speckle-tracking echocardiography is not without its limitations. Assessment of individuals with non-sinus heart rhythm can be challenging (early aorta biomechanics speckle-tracking studies excluded patients with atrial fibrillation [8, 72]). Furthermore, high-quality images including the area of interest wholly (the whole ventricle or vessel) for correct border delineation are necessary for accurate assessment [60]. It is also affected by the frame rate of the image loop, and comparatively poor lateral resolution might cause lateral dropout [53]. Lastly, the measurements depend on the specific make of the ultrasound machine, as they're not interchangeable between manufacturers [60].
Subclinical myocardial dysfunction in patients with complete recovery from peripartum cardiomyopathy: a long-term clinical strain-echocardiographic study
Published in Hypertension in Pregnancy, 2022
The value of EF for the assessment of LV function has been widely questioned during the past 10 years because of intrinsic limitations, including late reduction only in advanced stage of cardiovascular disease, poor reliability in patients with LV hypertrophy and volume reduction, interobserver variability due to apical foreshortening (19). In addition, EF only reflects the ventricular function indirectly and has a low sensitivity in terms of determining subtle LV systolic dysfunction (8–10). In this regard, several studies have successfully shown that speckle tracking echocardiography and strain analysis have better accuracy than two-dimensional echocardiography when compared using a reference technique, such as cardiac MRI (20). There is a growing body of evidence that the assessment of myocardial deformation using speckle-tracking techniques provides incremental information in the clinical setting. The applications for these techniques are in the assessment of myocardial mechanics, ischemic heart disease, and cardiomyopathies, and in detecting subclinical myocardial dysfunction in patients undergoing chemotherapy for cancer and transplant patients (21,22).
Assessment of biventricular function with speckle tracking echocardiography in newly-diagnosed adult-onset asthma
Published in Journal of Asthma, 2022
Sadettin Selçuk Baysal, Mehmet Has
Biventricular speckle tracking echocardiography analysis was performed using QLAB software (Philips Medical systems). While apical 4-chamber, 3-chamber, 2-chamber and long axis images were used for longitudinal strain analysis, parasternal short axis images (basal, papillary muscle level and apical) were used for circumferential strain analysis. Signs marking the endocardial margin were placed on the end-diastolic phase of the recordings, and then, region of interest (ROI) was automatically formed by the software as secondary concentric circle close to all endocardial segments and epicardium. Caution was exercised to include all of epicardium in the ROI. Left and right ventricular speckle tracking echocardiography data were calculated by automatic analysis of the movements of the speckles on the cardiac cycle (13). Mean strain value was calculated by summing end-diastolic strain values of 6 segments obtained on parasternal short axis, apical long axis, apical 4- and 2-chamber images and dividing this value by 6. Right and left ventricular global longitudinal strain value was determined by taking the mean longitudinal strain values of the apical 4-chamber, 2-chamber and long axis images, and left ventricular global circumferential strain value was determined by taking the mean segmental strain values of the parasternal short axis images. Right ventricular free wall strain (RV free) values were calculated manually by taking the mean of the measurements of 3 segments forming the right ventricular free wall (Figure 1) (18).
Assessment of subclinical left ventricular dysfunction with speckle-tracking echocardiography in hyperthyroid and euthyroid Graves’ disease and its correlation with serum TIMP-1
Published in Acta Cardiologica, 2021
Irfan Veysel Duzen, Suzan Tabur, Sadettin Ozturk, Mert Deniz Savcilioglu, Enes Alıc, Mustafa Yetisen, Sıddık Sanli, Huseyin Goksuluk, Ertan Vuruskan, Gokhan Altunbas, Fatma Yılmaz Coskun, Mehmet Kaplan, Seyithan Taysi, Murat Sucu
Speckle-tracking echocardiography has become widely available in the practice of cardiology. In contrast to tissue Doppler imaging (TDI), speckle-tracking echocardiography is independent of the angulation of the ultrasound beam and has low intra- and inter-operator variability. GLS is more sensitive to detect left ventricular dysfunction than LVEF. It is used for monitoring asymptomatic cardiotoxicity related to chemotherapy. GLS can be used in heart failure and valvular dysfunction It is clinically more useful than conventional echocardiography in detecting conditions such as hypertension and ischaemia. GLS gives prognostic information in asymptomatic left ventricular dysfunction caused by different diseases. Additionally, measurement of GLS shows less variability than left ventricular EF [3,4].