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Role of Plant-Based Anti-HIV Agents in HIV-Associated Neurocognitive Disorders (Hand)
Published in Megh R. Goyal, Preeti Birwal, Santosh K. Mishra, Phytochemicals and Medicinal Plants in Food Design, 2022
Vishal K. Singh, Himani Chaurasia, Richa Mishra, Ritika Srivastava, Vivek K. Chaturvedi, Ramendra K. Singh
The 6,8-diprenylaromadendrin and 6,8-diprenylkaempferol (both prenylate flavonoids) are extracted from Monotes Africanus and both exhibit anti-HIV action during XTT-based, whole-cell assessment. The gallate ester is obtained from Acer okamotoanum and it retards the progression of integrase enzyme of HIV-1 [39]. Methanolic extracts obtained from leaves and twigs of Rhus succedanea comprise of some polymerase inhibitors of HIV-1 that are named as Hinokiflavone, robustaflavone, and bioflavonoids [44]. Biflavonoid (e.g., Wikstrol-B) is extracted from roots of Wikstroemia indica and it also reveals activity against HIV [77]. A prenylchalcone (named as Xanthohumol) is extracted from hops of Humulus lupulus, and it demonstrates inhibitory action against HIV-1 replication [45, 74].
THE PROGRESS OF CHINESE MEDICINE IN TAIWAN
Published in Kevin Chan, Henry Lee, The Way Forward for Chinese Medicine, 2001
Chieh Fu Chen, Yau Chik Shum, Ming Tsuen Hsieh
erythrorhizon S. et Z. (^M), Litsea cubeba (Lour.) Persoon (ill iWffi), Rhamnus formosana Matsum. (niffi?), Wikstroemia indica C.A.Mey. (SSlSTt), Zanthoxylum schinifolium S. et Z. (), Corydalis ochotensis Turcz. (iKtUWS), Murraya
Arctigenin: pharmacology, total synthesis, and progress in structure modification
Published in Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Dan Wu, Lili Jin, Xing Huang, Hao Deng, Qing-kun Shen, Zhe-shan Quan, Changhao Zhang, Hong-Yan Guo
Natural products are a treasure house worthy of attention, and have great potential in the development of new drugs because of their rich sources. Arctigenin, a phenylpropane dibenzylbutyrolactone lignan isolated from Forsythia koreana, Saussurea heteromalla, Wikstroemia indica, Centaurea diluta, has been previously reported7. In the past research, arctigenin have made significant progress in determining the development of lead compounds for the treatment of human diseases and the research of related molecular mechanisms. Therefore, this article combines 75 pharmacological activities and 85 chemical related articles. Briefly reviews the pharmacology and total synthesis of arctigenin, and reviews the medicinal chemistry research progress of new derivatives of arctigenin, in order to understand the therapeutic potential and value of arctigenin.