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Medicinal Plants of the Trans-Himalayas
Published in Raymond Cooper, Jeffrey John Deakin, Natural Products of Silk Road Plants, 2020
Ajay Sharma, Garima Bhardwaj, Pushpender Bhardwaj, Damanjit Singh Cannoo
A profile by Tayade et al. (2013a) revealed the presence of 63 phytochemicals in the roots of R. imbricate. Salidroside and tyrosol (phenylethanoids) are the major bioactive compounds (Kapoor et al., 2018). Figure 3.13 shows the molecular structures of principal compounds of R. imbricate.
Quorum Sensing and Essential Oils
Published in K. Hüsnü Can Başer, Gerhard Buchbauer, Handbook of Essential Oils, 2020
Isabel Charlotte Soede, Gerhard Buchbauer
In 2001, Oh et al. identified farnesoic acid as another autoregulatory substance also inhibiting filamentous growth in a strain of C. albicans (Oh et al., 2001). Cho et al. showed that tyrosol is an autoregulatory molecule in C. albicans. Its effects are the shortening of the lag phase of diluted cultures, as well as the opposite effect of farnesol regarding germ tube formation—it accelerates the conversion from yeasts to mycelium (Cho et al., 2008).
Preclinical Antidepressant-Like Effects of Terpenes, Polyphenolics, and Other Non-Flavonoid Phytochemicals
Published in Scott Mendelson, Herbal Treatment of Major Depression, 2019
Salidroside is a glucoside of the simple phenolic compound tyrosol. Salidorside and rosavin are likely the active components of Rhodiola rosea.191 Sub-chronic treatment with salidroside attenuated the depression-like behaviors of mice injected with the inflammation-inducing lipopolysaccharide. Salidroside reduced levels of NF-kβ, and attenuated the lipopolysaccharide-induced decreases in serotonin and norepinephrine in the frontal cortex. Salidroside also increased expression of BNDF and TrkB in the hippocampus.192
Antihyperlipidemic effect of tyrosol, a phenolic compound in streptozotocin-induced diabetic rats
Published in Toxicology Mechanisms and Methods, 2021
Ramasamy Chandramohan, Leelavinothan Pari
Tyrosol is a phenolic compound found especially in olive and olive oil, wine, and several other herbal products. The tyrosol content of olive oil varies, depending on the cultivar, climate, ripeness of the olives at harvesting, and the processing system employed to produce the olive oil. The concentration of tyrosol in olive oil has been reported to be 4.69 ± 0.77 mg/kg (Coni et al. 2000); and 27.45 ± 4.05 mg/kg in extra-virgin olive oil and 2.98 ± 1.33 mg/kg in refined virgin oil (Owen et al. 2000). The concentration of tyrosol content in red wines has also been reported, ranging from 20.51 to 44.46 mg/L (Piñeiro et al. 2011).